Health databases & datasets: Europe

HDB-0047

ArrayExpress (BioStudies)

European Molecular Biology Laboratory (EMBL), European Bioinformatics Institute ArrayExpress is a repository for functional genomics experiments including array and sequence-based studies, housed within the BioStudies database at EMBL-EBI. Researchers can browse, submit, and download experimental metadata, protocols, and data files through web interfaces or specialized tools like the Bioconductor package and Annotare submission system. Open dataset Open access HDB-0065

Eurostat Health Database

Eurostat (European Commission) Eurostat's health database provides statistical information on health and health systems across EU member states and associated countries. It covers health expenditure, resources, activities, and services with data structured by topic and accessible through interactive tools and bulk download. Open dataset Open access HDB-0070

CBS StatLine Health

CBS (Centraal Bureau voor de Statistiek - Statistics Netherlands) CBS StatLine is the electronic database of Statistics Netherlands providing open access to official Dutch statistics on health and welfare topics. Users can create custom tables and download health data at no cost; microdata access requires authorization. Open dataset Open access HDB-0071

Vektis Open Data

Vektis (Dutch healthcare information organization) Vektis manages healthcare cost data from the Dutch Health Insurance Act, providing aggregated open datasets on healthcare spending by service type at postal code and municipal levels. Data is freely downloadable as CSV files with annual updates covering 2011-2024. Open dataset Open access HDB-0111

Turkish Statistical Institute (TUIK) Health Statistics Portal

Turkish Statistical Institute (TUIK) The Turkish Statistical Institute maintains a comprehensive health statistics portal with aggregated data on Turkey's population health including mortality, morbidity, health expenditure, disability, and healthcare utilization statistics. The portal provides public access to downloadable datasets and indicators covering health and social protection statistics compiled from national health surveillance systems. Open dataset Open access HDB-0122

SNDS (Système National des Données de Santé)

Cnam (National Health Insurance Fund) The SNDS integrates health insurance reimbursement data (Sniiram), hospital activity records (PMSI), mortality data from Inserm, and disability support data, covering over 65 million individuals. Access is provided through the Health Data Hub to public organizations with permanent public service missions and to entities authorized by CNIL (France's data protection authority) for public interest research. Research database Credentialed HDB-0123

Health Data Hub (Plateforme des données de santé)

GIP Santé (Public Interest Grouping), joint supervision of Ministry of Health, INRIA, INSERM, CNAM The Health Data Hub is France's national platform providing secure, unified access to pseudonymized health data from SNDS and other national health registries, serving researchers, innovators, and public health authorities. Data access requires project submission, CNIL authorization, and demonstration of public interest; over 230 projects have been approved through the platform. Research database By application HDB-0124

Forschungsdatenzentrum Gesundheit (FDZ Gesundheit)

BfArM (Federal Institute for Drugs and Medical Devices) The FDZ Gesundheit provides pseudonymized billing data from all legally insured Germans through virtual analysis workspaces, with plans to add electronic patient record (ePA) data as of late 2026. Researchers submit applications detailing their research purpose, and approved researchers access customized datasets within secure analysis environments without direct data transfer. Research database By application HDB-0125

German Centre for Cancer Registry Data (Zentrum für Krebsregisterdaten, ZfKD)

Robert Koch Institute (RKI) The ZfKD consolidates clinical and epidemiological cancer registry data from all 16 German federal states, providing incidence, prevalence, and survival statistics across 30+ cancer types with 25 years of historical data. Access is provided through an interactive database query interface and regular epidemiological publications; data through 2023 is available. Research database Open access HDB-0126

PHARMO Database Network

PHARMO Institute (now part of Lumanity) The PHARMO Database Network comprises anonymized linked healthcare records from 14 million patients across 1,400 primary and secondary care providers in the Netherlands, representing 250 million person-years of data including GP records, hospital admissions, pharmacy records, and specialized registries. Researchers access PHARMO through coordinated studies via institutional partnerships; the database has contributed to over 1,000 published studies covering drug safety, effectiveness, and utilization. Research database Credentialed HDB-0127

Nivel Primary Care Database (Nivel-PCD)

Nivel (Netherlands Institute for Health Services Research) The Nivel Primary Care Database combines routine electronic health record data from representative samples of Dutch primary care providers (GPs, physiotherapists, mental health professionals, dietitians) linked with pharmacy and secondary care data. Researchers access de-identified data through a formal application and approval process governed by steering committees with healthcare provider representatives. Research database Credentialed HDB-0128

Healthdata.be / Health Data Agency (HDA)

Health Data Agency (formerly Sciensano) Healthdata.be is a Belgian platform that facilitates data exchange between healthcare professionals and researchers while protecting privacy and medical confidentiality, providing inventory of national health registries and secure data collection infrastructure. As of April 1, 2026, the platform is managed by the Health Data Agency; access procedures and registry management are coordinated through the updated platform at hda.belgium.be. Research database By application HDB-0138

Hospital In-Patient Enquiry (HIPE)

Healthcare Pricing Office (HPO), Irish Department of Health HIPE is a national computerised health information system recording demographic, administrative, and clinical data on all inpatient and daycase discharges from publicly funded acute hospitals in Ireland, covering approximately 1.7 million discharges annually from 58 public acute hospitals. Researchers access HIPE data through the HPO for health services research, epidemiology, clinical audit, and policy planning using the HIPE Statistics Reporter or data requests. Research database By application HDB-0148

EudraCT

European Medicines Agency (EMA) EudraCT is the European Union's database for interventional clinical trials on medicinal products conducted in the EU/EEA from May 2004 through January 2025 under Directive 2001/20/EC. As of January 31, 2025, new EU/EEA trials must transition to the newer Clinical Trials Information System (CTIS), though EudraCT continues to accept results submissions and third-country trial files. Trial registry Open access HDB-0149

EU Clinical Trials Register

European Medicines Agency (EMA) The EU Clinical Trials Register provides public access to information on trials previously registered in EudraCT, including trial protocols and results data. It serves as the historical and transitional repository for EU/EEA trial information while ongoing trials are registered through the newer Clinical Trials Information System. Trial registry Open access HDB-0155

EHDEN

EHDEN Foundation EHDEN operates a federated network of over 100 healthcare data sources across Europe standardized to the OMOP Common Data Model to generate reliable real-world evidence for medicines and health research. The foundation provides infrastructure, training, and research coordination services to enable collaborative studies while maintaining data governance and institutional autonomy. Research database By application HDB-0156

DARWIN EU

European Medicines Agency (EMA) DARWIN EU is the EMA's Data Analysis and Real World Interrogation Network, established to provide timely evidence on the safety and effectiveness of medicines using real-world healthcare data from approximately 40 data partners across the EU. The network conducts regulatory studies to support medicines oversight and authorization decisions throughout a medicine's lifecycle. Research database By application HDB-0164

SHARE (Survey of Health, Ageing and Retirement in Europe)

SHARE-ERIC (European Research Infrastructure Consortium) Europe's largest social science panel study collecting longitudinal data on health, biomarkers, employment, cognition, and economics across 28 participating countries. Researchers register as users and access data through the dedicated data portal (share-project.org/data), with approximately 690,000 interviews from 175,000 respondents supporting over 4,800 publications. Open dataset Free registration HDB-0166

Lifelines (Dutch Biobank and Cohort Study)

Lifelines Biobank, University Medical Center Groningen The Netherlands' largest biobank with over 167,000 participants providing health data and biological samples approximately every five years. Researchers submit data access applications through the dedicated biobank portal (lifelines-biobank.com), gaining access to well-organized questionnaires and datasets supporting over 750 scientific publications. Open dataset By application HDB-0168

German National Cohort Study (NAKO)

German Federal Ministry of Education and Research and participating research institutions Germany's largest long-term study researching common diseases with participants undergoing ongoing examinations and health questionnaires in multiple phases. Researchers can access information through the NAKO TransferHub and contact research-responsible persons for collaboration, with resources supporting multiple research projects and an International NAKO Conference planned for 2026. Open dataset By application HDB-0177

CAMELYON17

Diagnostic Image Analysis Group (DIAG), Radboud University Medical Center; Department of Pathology, Leiden University Medical Center An open-access histopathology dataset of 1,399 H&E-stained whole-slide images of sentinel lymph nodes from breast cancer patients, created for automated detection and classification of metastases. The dataset includes training and test sets with pixel-level annotations. Open dataset Open access HDB-0233

Russia Longitudinal Monitoring Survey—Higher School of Economics (RLMS-HSE)

Higher School of Economics University; Carolina Population Center, University of North Carolina at Chapel Hill A nationally representative panel survey conducted annually since 1994 tracking health, economic welfare, employment, income, education and lifestyle for Russian households and individuals. Data are freely available for public analysis in Stata and SPSS formats with codebooks and questionnaires in English. Research database Free registration HDB-0234

Federal Diabetes Register (Diaregistry)

National Medical Research Center of Endocrinology; Russian Ministry of Health A clinical-epidemiological monitoring system tracking diabetes mellitus, hypothalamic-pituitary tumors, hypoparathyroidism, primary hyperparathyroidism, and medullary thyroid cancer across all 83 Russian regions. The registry integrates patient data from healthcare facilities nationwide to support surveillance and clinical research on endocrine conditions. Research database Credentialed HDB-0236

WHO European Health Information Gateway

World Health Organization Europe A central data repository for validated health, economic and demographic statistics across the 53 countries in the WHO European Region, including Russia, Central Asia, Caucasus and Eastern Europe. Covers ~1,450 indicators on health status, risk factors, health systems and resources with data spanning 1970 to present. Research database Open access HDB-0243

Russian Federation Country Health Profile — WHO Data

World Health Organization WHO's health dataset for the Russian Federation including population, life expectancy, mortality by cause, disease burden, immunization coverage and health workforce density. Data support international health comparison and disease surveillance. Research database Open access HDB-0245

Russian Research Institute of Health (Mednet) — Health Statistics Department

Russian Research Institute of Health; Russian Ministry of Health Russia's health policy and research institute maintains a database of statistical observation forms from all 83 regions using the MEDSTAT software package. Provides data on health status, health system performance and epidemiological indicators across the Russian Federation. Research database Credentialed HDB-0246

National Health Fund (NFZ)

Narodowy Fundusz Zdrowia (NFZ), Ministry of Health of Poland Poland's state health insurance administrator that finances universal healthcare and maintains administrative data on inpatient, outpatient and pharmacy services. NFZ publishes open data through the Zdrowe Dane portal covering healthcare utilization, costs, and service quality metrics at facility level. Open dataset Free registration HDB-0247

Statistics Poland (GUS) — Health Statistics

Główny Urząd Statystyczny (GUS), Central Statistical Office of Poland Poland's national statistics office publishes official health statistics including mortality, morbidity, healthcare workforce, and epidemiological data. Data is freely accessible online and used by researchers, policymakers and international organizations. Open dataset Open access HDB-0248

Institute of Health Information and Statistics (ÚZIS ČR) — National Health Information System

Ústav zdravotnických informací a statistiky (ÚZIS ČR), Ministry of Health of the Czech Republic Established in 1960, ÚZIS maintains the Czech Republic's National Health Information System and 12 national health registries covering cancer, hospitalization, reproduction health, cardiovascular surgery, occupational diseases, and other conditions. Data is published in the Czech Health Statistics Yearbook and provided to researchers through formal requests. Research database Credentialed HDB-0249

National Health Insurance Fund (NEAK)

Nemzeti Egészségbiztosítási Alapkezelő (NEAK), Ministry of the Interior of Hungary Hungary's state health insurance fund manages the universal healthcare system and maintains administrative data on publicly funded health services, pharmaceuticals, and medical devices. NEAK publishes monthly traffic data, utilization analyses, and waiting list statistics. Open dataset Free registration HDB-0250

National Institute of Public Health (NIJZ)

Nacionalni inštitut za varovanje zdravja (NIJZ), Ministry of Health of Slovenia NIJZ is Slovenia's principal public health authority maintaining health registries and databases on communicable diseases, vaccinations, occupational accidents, hospitalization and outpatient services. Data collection uses the automated e-transfer portal ePrenosi with real-time data validation and feedback to providers. Research database Credentialed HDB-0251

Croatian Institute of Public Health (HZJZ)

Hrvatski zavod za javno zdravstvo (HZJZ), Ministry of Health of Croatia HZJZ is the official carrier of health statistics in Croatia and maintains national registries on cancer, diabetes, communicable diseases and occupational diseases. The Institute publishes annual health-statistical yearbooks and thematic epidemiological reports used by policymakers and researchers. Research database Open access HDB-0252

National Health Information Center (NCZI)

Národné centrum zdravotnických informácií (NCZI), Ministry of Health of the Slovak Republic NCZI is Slovakia's state-funded organization administering the National Health Information System and national health registries covering administrative and clinical data from healthcare providers. The center standardizes health informatics, compiles health statistics and collaborates internationally with WHO, OECD and EUROSTAT. Research database Credentialed HDB-0253

National Health Information System (NHIS)

Ministry of Health of Bulgaria Bulgaria's centralized electronic health record platform storing and exchanging medical information among healthcare stakeholders with standardized data formats and unified medical terminology coding. As of July 2026, the system contains 764.7 million electronic health documents, 204+ million e-examinations, and provides patient access through the eZdrave portal. Open dataset Free registration HDB-0254

Institute of Public Health of Serbia 'Dr Milan Jovanović Batut'

Institut za javno zdravlje Srbije 'Dr Milan Jovanović Batut', Ministry of Health of Serbia Serbia's expert public health institution maintains databases on health and healthcare utilization, national health registries, and conducts population health surveys. The Institute provides independent research on public health issues and technical guidance to the Serbian government on health policy and services planning. Research database Credentialed HDB-0255

Ukraine National eHealth System

Ministry of Health of Ukraine Ukraine's centralized national eHealth system operating since March 2019 and serving 36.5+ million users, connecting healthcare institutions and providers via a HL7 FHIR-based infrastructure. The system manages electronic health records, e-prescriptions, e-referrals and provides MedData integration for administrative and clinical data from the healthcare system. Open dataset Free registration HDB-0256

Estonian e-Health Foundation — National Health Information System

Estonian e-Health Foundation (EeHF), Ministry of Social Affairs of Estonia Estonia's centralized national health information system, operational since 2008, securely stores and retrieves 40+ million health documents from diverse healthcare providers via the e-Patient portal accessible through public e-ID. The Health Board (Terviseamet) registers healthcare professionals and maintains communicable disease surveillance alongside the e-Health Foundation's management of integrated provider systems and nationwide health registries. Open dataset Free registration HDB-0257

National Health Service (VMNVD) — e-Health System

Nacionālais veselības dienests (VMNVD), Ministry of Health of Latvia Latvia's national e-health system (www.eveseliba.gov.lv) provides patients and medical personnel authorized access to medical information with WHO security certification. VMNVD maintains registries of medical institutions and professionals, manages electronic data exchange including cross-border health data access, and publishes health data analysis for payment and planning purposes. Open dataset Free registration HDB-0259

Turkish Statistical Institute (TÜİK)

Turkish Statistical Institute (Türkiye İstatistik Kurumu) Turkey's official statistical authority publishing comprehensive demographic, epidemiological, and health statistics including mortality data, morbidity indicators, and healthcare utilization. Data is freely accessible through the institute's Data Portal (Veri Portalı) and thematic statistical tables. Open dataset Open access HDB-0260

Turkey Demographic and Health Survey (TDHS)

Hacettepe University Institute of Population Studies A nationally representative population and health survey conducted at five-year intervals since 1993 by Hacettepe University, providing data on fertility, maternal and child health, family planning, and early childhood development across Turkey. Microdata is available to researchers through formal data-sharing agreements. Research database Credentialed HDB-0261

Turkey Ministry of Health Health Statistics Yearbook

Turkish Ministry of Health (T.C. Sağlık Bakanlığı) Annual official yearbooks published by the Ministry of Health containing detailed health statistics on mortality, morbidity, disease prevention, healthcare facilities, medical personnel, and health financing across Turkey. Data is freely available through the ministry's website and the Sağlık Bakanlığı Open Data Portal (acikveri.saglik.gov.tr). Open dataset Open access HDB-0267

WHO Health for All Database (HFA-DB)

WHO Regional Office for Europe Core health statistics database of the WHO European Region containing approximately 1,450 indicators across demographics, health status, determinants, and health care resources for 53 European member states. Data spans from 1970 to present and is updated annually based on member state reporting, allowing integrated access and dynamic cross-country comparisons. Open dataset Open access HDB-0268

ECDC Surveillance Atlas of Infectious Diseases

European Centre for Disease Prevention and Control (ECDC) Interactive mapping tool providing access to surveillance data on infectious diseases across EU/EEA member states. Users can browse disease data by country and time period, create custom maps and tables, and export results in multiple formats. Open dataset Open access HDB-0269

European Cancer Information System (ECIS)

European Commission Joint Research Centre (JRC), in collaboration with European Network of Cancer Registries (ENCR) Web-based tool aggregating cancer burden data from approximately 150 population-based cancer registries across 34 European countries, covering 58 cancer sites. Provides incidence, mortality, prevalence, and survival estimates updated as new registry data become available. Research database Open access HDB-0271

Euro-Peristat: European Perinatal Health Report

Inserm (French National Institute of Health and Medical Research), Paris; funded by European Commission European perinatal surveillance network coordinating data collection on mothers' and newborns' health outcomes from 31 countries across vital statistics, medical birth registers, and hospital discharge data. Publishes periodic European Perinatal Health Reports (2008, 2013, 2018, 2022) and national-level data on stillbirth, preterm birth, neonatal mortality, and socioeconomic health disparities. Research database Open access HDB-0272

ESPAD: European School Survey Project on Alcohol and Other Drugs

Coordinated by independent research teams across Europe (40+ participating countries) Largest cross-national research project on adolescent substance use in Europe, collecting comparable data from 15–16-year-old students every four years since 1995 across 37+ countries. The data portal provides access to trends in tobacco, alcohol, and illicit drug use alongside mental well-being, gaming, and social media use indicators. Open dataset Open access HDB-0274

European Social Survey (ESS) with Health Modules

European Research Infrastructure Consortium (ERIC); coordinated from multiple European research institutions High-quality open-access survey of public attitudes, beliefs, and behavior across 30+ European countries conducted biennially since 2002, with rotating topical modules including dedicated health rounds. Health modules in Round 2 (2004/05) and Round 7 (2014/15) examined health-seeking behavior and social determinants of health inequality, with Round 11 (2023/24) focusing on health inequalities in the post-COVID era. Research database Free registration HDB-0295

CTIS (Clinical Trials Information System)

European Medicines Agency (EMA) CTIS is the European Medicines Agency's system through which sponsors apply to run a clinical trial and manage an ongoing trial across up to 30 EU and EEA countries, launched on 31 January 2022. It replaced EudraCT for new trials and publishes information on individual trials in the EU and EEA through a public search interface. Trial registry Open access HDB-0298

DRKS (German Clinical Trials Register)

Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) DRKS is the WHO-recognised primary register for Germany, operated by the Federal Institute for Drugs and Medical Devices (BfArM), and registers health-related studies conducted in Germany on human subjects. Its search is publicly accessible and researchers register their studies through a separate registration portal. Trial registry Open access HDB-0319

European Genome-phenome Archive (EGA)

EMBL-EBI and CRG The EGA archives individual-level genomic and phenotypic data from biomedical studies, operated jointly by EMBL-EBI and the Centre for Genomic Regulation. Researchers request datasets from the data access committee of each study, which grants access under the study's consent terms. Open dataset By application HDB-0370

Cegedim Health Data — THIN

Cegedim THIN (The Health Improvement Network) contains longitudinal de-identified primary care electronic health records collected by Cegedim Health Data from practices in several European countries including France, the United Kingdom, Spain, Belgium, Romania and Italy. Pharmaceutical companies, health authorities and academic researchers license it for real-world evidence, drug safety and health economics research. Commercial provider Paid HDB-0371

Insight Health

Insight Health / CompuGroup Medical Insight Health licenses pharmaceutical market data derived from German statutory health insurance claims, covering prescriptions, over-the-counter products, medical devices and hospital records. Pharmaceutical companies, research organisations and health authorities license it for market analysis and health economics research. Commercial provider Paid HDB-0431

TUYZE (Türkiye Health Data Research and AI Applications Institute)

Health Institutes of Türkiye (TUSEB) A government research institute focused on health data analysis and artificial intelligence applications in healthcare, operating three specialized departments: Big Data, Medical Decision Support Systems, and Smart Medical Device Technologies. The institute develops data-driven healthcare solutions and conducts research on Turkish health datasets. Research database Credentialed HDB-0467

Estonian Biobank

University of Tartu, Institute of Genomics The Estonian Biobank is a population-based biobank holding genotype data and health information for a substantial share of Estonia's adult population, run by the Institute of Genomics at the University of Tartu. It stores DNA, plasma and serum alongside linked national health-registry data, and researchers apply for access for approved studies. Open dataset By application HDB-0497

ECRIN Clinical Research Data Sharing Repository

European Clinical Research Infrastructure Network (ECRIN) A Trusted Research Environment operated by ECRIN that supports sharing of anonymised and pseudonymised individual participant data from clinical research studies in compliance with EU legislation. The repository hosts datasets, study protocols, analysis plans, and consent templates to facilitate secure access and meta-analyses across European clinical research. IPD repository Credentialed HDB-0500

EMA Clinical Data Publication Portal

European Medicines Agency A publicly accessible repository of clinical trial data submitted by pharmaceutical companies to support regulatory applications for centrally authorised medicines, including clinical study reports, overviews, summaries, study protocols, and case report forms. Researchers and regulators can access published clinical datasets by registering an EMA account, with options for on-screen viewing or download. Research database Free registration HDB-0505

Batut (Institute of Public Health of Serbia "Dr Milan Jovanović Batut")

Serbian Ministry of Health Batut maintains Serbia's health indicators database and disease registries, collecting data on health and healthcare utilization from the national health system. The institute provides a Data Presentation System enabling users to access health statistics and indicators by geographic area and disease. Research database Open access HDB-0506

Public Health Center of Ukraine

Ukrainian Ministry of Health The Public Health Center maintains Ukraine's epidemiological surveillance systems and disease registries tracking infectious diseases including measles, tuberculosis, and HIV/AIDS. The center collects operational epidemiological data through weekly reporting mechanisms and coordinates national immunization programs. Research database Open access HDB-0507

EHIF (Estonian Health Insurance Fund)

Estonian Government The Estonian Health Insurance Fund (Tervisekassa) administers Estonia's social health insurance system and maintains an administrative claims database covering health service contacts, prescription medicines and medical device records. Its data are integrated into Estonia's eHealth infrastructure and the national health portal (Terviseportaal), and researchers apply to the fund for access. Research database By application HDB-0508

SPKC (Centre for Disease Prevention and Control, Latvia)

Latvian Ministry of Health SPKC maintains Latvia's Health Statistics Database and infectious disease registries including HIV/AIDS, tuberculosis, and vaccination records. The center produces epidemiological bulletins and annual statistical reports on infectious and parasitic diseases alongside patient-reported experience measurements and healthcare facility performance indicators. Research database Open access HDB-0510

e-zdrowie (Polish Health Information Portal)

Polish Ministry of Health / Centre for e-Health e-zdrowie serves as Poland's central health information platform providing medical registers, health data reports, and statistics from the National Health Fund (NFZ) and other national health institutions. The portal includes the Medical Registers Platform for electronic document exchange and access to comparative health analyses covering insurance, providers, and waiting times. Open dataset Open access HDB-0511

Maps of Health Needs (Mapy Potrzeb Zdrowotnych, Poland)

Polish Ministry of Health Maps of Health Needs is Poland's interactive health data platform consolidating data from multiple national health sources including NFZ, NIZP-PZH, Centre for e-Health, and the Central Statistical Office. The platform enables cross-sectional analysis of health data and healthcare capacity at regional and local levels. Open dataset Open access HDB-0513

EU Trials Tracker

Bennett Institute for Applied Data Science, University of Oxford A monitoring platform tracking compliance with European Union clinical trial result reporting requirements, which mandate that trials on the European Union Clinical Trials Register (EUCTR) report results within one year of completion. The tracker displays reporting percentages for sponsors and identifies institutions meeting or falling behind on reporting obligations. Trial registry Open access HDB-0514

OMON (Overview of Medical Research in the Netherlands)

Central Committee on Research Involving Human Subjects (CCMO) A centralized Dutch registry consolidating clinical trial and medical research data from multiple sources including the former National Trial Register (NTR), ToetsingOnline, the Research Portal, and CTIS public data. The platform serves both research participants seeking studies to join and researchers needing to register, submit and manage medical research. Trial registry Open access HDB-0544

EUROCARE: Cancer Survival in Europe

Istituto Nazionale dei Tumori (National Cancer Institute), Milan; Istituto Superiore di Sanità (Italian National Institute of Health), Rome EUROCARE is a collaborative study of population-based cancer survival in Europe, running since 1989 and coordinated by the Istituto Superiore di Sanità, which pools and standardises data contributed by national and regional cancer registries. Its published analyses compare survival trends and between-country variation, and aggregated results are freely available from the project website. Research database Open access HDB-0560

InGef Research Database

InGef — Institut für angewandte Gesundheitsforschung Berlin InGef, the Institute for Applied Health Research Berlin, maintains an anonymised research database of German statutory health insurance billing data covering outpatient and inpatient care, drug prescriptions and sociodemographics, longitudinally linked over several years. It is used for health-services research and pharmacoepidemiological studies, which InGef conducts on commission for industry, academic and public clients. Commercial provider Paid HDB-0563

ISTAT Health for All - Italia

ISTAT (Italian National Institute of Statistics) Health for All – Italia is an interactive indicator database published by ISTAT, the Italian national statistics institute, covering health status, healthcare resources, service use and social determinants. Indicators can be browsed and downloaded at national and regional level without registration. Open dataset Open access HDB-0564

Ministero della Salute Open Data Portal

Ministero della Salute (Italian Ministry of Health) The open data portal of Italy's Ministry of Health publishes administrative datasets on healthcare personnel, hospital beds, hospital admissions, medical equipment and devices. Files are downloadable without registration in CSV, JSON and XML. Open dataset Open access HDB-0565

AIFA OsMed - Medicines Utilization Monitoring Centre

AIFA (Italian Medicines Agency) OsMed is the medicines-use monitoring service of AIFA, the Italian Medicines Agency, reporting pharmaceutical consumption and expenditure in Italy. The interactive interface allows queries and national-to-regional comparisons without registration. Open dataset Open access HDB-0566

AIRTUM - Italian Association of Cancer Registries

AIRTUM (Associazione Italiana Registri Tumori) AIRTUM is the association coordinating Italy's population-based cancer registries and maintains the pooled national dataset of cancer incidence, mortality and survival. Aggregated figures are published openly; record-level data are obtained from the member registries under agreement. Research database Credentialed HDB-0567

RIAP - Registro Italiano di ArtroProtesi (Italian Arthroplasty Registry)

ISS (Istituto Superiore di Sanità) / Ministry of Health RIAP is Italy's national arthroplasty registry, run by the Istituto Superiore di Sanità for the Ministry of Health, recording hip, knee, shoulder and ankle joint-replacement procedures and the implants used. It supports device safety surveillance and post-market monitoring; data are made available to participating regions and researchers through the registry. Research database Credentialed HDB-0568

Regione Lombardia Open Data Portal - Health

Regione Lombardia (Lombardy Regional Government) The Lombardy regional government's open data portal publishes datasets from the regional administration, including health and epidemiological data drawn from its regional data warehouse. Datasets are downloadable without registration; licence terms are stated per dataset and are not specified for all of them. Open dataset Open access HDB-0569

Emilia-Romagna ReportER - SISEPS Health Data Portal

Regione Emilia-Romagna (Emilia-Romagna Regional Government) ReportER is the public reporting interface to SISEPS, the health and social policy information system of the Emilia-Romagna region. It publishes regional health indicators for consultation without registration. Open dataset Open access HDB-0570

National Registry of Congenital Malformations (RNMC)

ISS (Istituto Superiore di Sanità) / Ministry of Health The National Registry of Congenital Malformations, held at the Istituto Superiore di Sanità, records structural birth defects detected prenatally, at birth and during the first year of life. It underpins national surveillance and contributes to European birth-defect monitoring; data are obtained from the registry under agreement. Research database Credentialed HDB-0571

EpiCentro - Epidemiological Information Gateway

ISS (Istituto Superiore di Sanità) EpiCentro is the epidemiology portal of the Istituto Superiore di Sanità, giving access to Italy's surveillance systems, disease registries and epidemiological reporting on communicable and non-communicable disease. Surveillance outputs and reports are published openly. Open dataset Open access HDB-0572

PASSI - Adult Behavioural Risk Factor Surveillance System

ISS (Istituto Superiore di Sanità) PASSI is a continuous behavioural risk factor surveillance system run by the Istituto Superiore di Sanità, which interviews adults aged 18–69 about health determinants and preventive care. Results are published as national, regional and local indicators without registration. Open dataset Open access HDB-0573

CMBD / RAE-CMBD

Ministerio de Sanidad, Consumo y Bienestar Social RAE-CMBD is Spain's hospital discharge database, compiled by the Ministry of Health from the minimum basic data set reported by National Health System hospitals. Aggregate statistics on admissions, procedures and outcomes are published; record-level extracts are supplied to authorised requesters. Open dataset Credentialed HDB-0574

BIFAP

Spanish Agency for Medicines and Medical Devices (AEMPS) BIFAP is a pharmacoepidemiological database of primary care electronic medical records, operated by AEMPS, the Spanish agency for medicines and medical devices. It is used for drug safety and drug utilisation research; researchers apply to the agency for access. Research database By application HDB-0575

SIDIAP

Catalan Health Institute (Institut Català de la Salut) SIDIAP holds primary care electronic health records from the Catalan Health Institute's practice network, including diagnoses, prescriptions, laboratory results and vaccinations. Researchers apply for access for epidemiological and health services research. Research database By application HDB-0576

REDECAN

Spanish Network of Population-Based Cancer Registries REDECAN is the network of Spain's population-based cancer registries, including childhood cancer registries, which pools regional data into national incidence, survival and prevalence estimates. Aggregate results are published openly. Open dataset Open access HDB-0577

Spain Health Survey (ESdE)

Ministerio de Sanidad and Instituto Nacional de Estadística (INE) The Encuesta Nacional de Salud is Spain's national health survey of private households, run by the Ministry of Health with the national statistics institute, covering health status, use of health services and health determinants. Results and microdata are published openly. Open dataset Open access HDB-0578

INE Spain Health Statistics (INEbase)

Instituto Nacional de Estadística (INE) INE, Spain's national statistics institute, publishes the health section of INEbase, covering health status, hospital activity, health professionals, pharmaceuticals and mortality. Tables and microdata are downloadable without registration and are also served through the institute's API. Open dataset Open access HDB-0579

SNS Transparência Portal

Serviço Nacional de Saúde (SNS) / SPMS The Portal da Transparência of Portugal's Serviço Nacional de Saúde publishes operational data on the public health service, including hospital activity, waiting times and emergency department attendance. Datasets are browsable and downloadable without registration and are also served through an API. Open dataset Open access HDB-0580

Destatis Health Statistics

Federal Statistical Office (Statistisches Bundesamt) Destatis, the German Federal Statistical Office, publishes the official national health statistics, covering health status, health expenditure, use of services and healthcare facilities. Tables are available without registration. Open dataset Open access HDB-0581

GePaRD

Leibniz Institute for Prevention Research and Epidemiology – BIPS GePaRD is a claims database held at BIPS, the Leibniz Institute for Prevention Research and Epidemiology, built from the routine data of German statutory health insurers. It is used for pharmacoepidemiology and health services research; studies are carried out in collaboration with the institute under data protection approval. Research database Credentialed HDB-0582

Statistik Austria Health Statistics

Statistics Austria (Statistik Austria) Statistics Austria publishes national health data through its STATcube database and STATatlas interfaces, covering health status, health expenditure and healthcare facilities. Overview tables are free to consult; detailed extracts require a registered or paid account. Open dataset Free registration HDB-0583

NICER

National Institute for Cancer Epidemiology and Registration NICER is the Swiss foundation that coordinates the cantonal cancer registries and holds the harmonised national cancer dataset; since 2018 it has been mandated to carry out the tasks of the National Cancer Registration Agency (NKRS) under the Cancer Registration Act. It publishes national incidence and mortality statistics and supplies data to researchers on request. Research database Credentialed HDB-0584

Swiss National Cohort

University of Bern, Epidemiology, Biostatistics and Prevention Institute (EBPI) The Swiss National Cohort is a longitudinal study of the resident population of Switzerland built by linking census records to mortality and migration follow-up. Researchers apply for access for studies of health inequalities, mortality and health policy. Research database Credentialed HDB-0585

Swiss Federal Statistical Office Health Statistics

Federal Statistical Office (Bundesamt für Statistik / Office fédéral de la statistique) The Swiss Federal Statistical Office publishes the national health statistics, covering health status, chronic disease, health determinants, use of services and health expenditure. Tables are available without registration as part of the official statistics programme. Open dataset Open access HDB-0586

Odissé

Santé publique France Odissé is the open data platform of Santé publique France, publishing public health indicators and disease surveillance data. Data are available through a web interface and an API without registration. Open dataset Open access HDB-0587

Data.DREES

DREES (Direction de la Recherche, des Études, de l'Évaluation et des Statistiques) Data.DREES is the open data platform of DREES, the statistical directorate of the French health and social affairs ministry, covering the healthcare system, social protection, long-term care, disability and pensions. Datasets are downloadable and explorable without registration. Open dataset Open access HDB-0588

CASD (Centre d'Accès Sécurisé aux Données)

CASD The Centre d'accès sécurisé aux données gives researchers controlled access to French public statistical and health datasets inside an isolated secure environment. Access is granted per project on application and all use is audited. Research database Credentialed HDB-0589

INCa National Cancer Registry

Institut National du Cancer (INCa) The Institut national du cancer publishes French cancer data covering incidence, screening, treatment activity and survival. Aggregated indicators are open; access to detailed data runs through application to the institute. Research database By application HDB-0590

Belgian Cancer Registry

Belgian Cancer Registry Foundation The Belgian Cancer Registry is the national registry that collects every new cancer diagnosis in Belgium, coordinating reporting across Flanders, Wallonia and Brussels. Aggregate statistics are published; researchers apply to the registry for data. Research database By application HDB-0591

Netherlands Heart Registration (NHR)

Netherlands Heart Registration The Nederlandse Hart Registratie collects data on invasive cardiac, electrophysiological and cardiac surgical procedures performed at participating Dutch hospitals. It is used for quality monitoring of cardiac care; researchers apply to the registry for data. Research database By application HDB-0592

Lifestyle Monitor

RIVM (National Institute for Public Health and the Environment) The Leefstijlmonitor is a partnership led by RIVM that tracks lifestyle and health behaviour in the Dutch population through recurring surveys, covering smoking, alcohol, diet and physical activity. Aggregated national and regional indicators are published without registration. Open dataset Open access HDB-0621

Forschungsdatenportal für Gesundheit (FDPG)

Medical Informatics Initiative (MII), Germany The German Research Data Portal for Health is the central point of contact through which scientists request pseudonymised patient data and biosamples held by the university hospitals of Germany's Medical Informatics Initiative. Researchers run a feasibility query and then submit a data use application that the participating sites review. Research database By application HDB-0623

ERN-RND Registry

European Reference Network on Rare Neurological Diseases (ERN-RND), hosted by University Hospital Tübingen The ERN-RND Registry collects standardised patient data from the network's expert centres across six groups of rare neurological diseases — ataxias, choreas, dystonias, frontotemporal dementia, leukodystrophies and atypical parkinsonism — and is hosted by University Hospital Tübingen. A Data Access Committee reviews requests from clinicians, researchers, health authorities and patient organisations for aggregated or pseudonymised patient-level data. Research database By application HDB-0626

RD-Connect Genome-Phenome Analysis Platform (GPAP)

RD-Connect GPAP The RD-Connect Genome-Phenome Analysis Platform lets authorised users submit, share and analyse genomic and phenotypic data from rare disease patients and their relatives, to support diagnosis and gene discovery, and is an IRDiRC Recognized Resource. Access requires registration and authorisation as a platform user. Research database Credentialed HDB-0627

SurvStat@RKI

Robert Koch Institute (RKI) SurvStat@RKI is the Robert Koch Institute's public query interface to Germany's notifiable infectious disease surveillance data, reported under the Infection Protection Act. Users build their own queries on cases by disease, region and time period and export the resulting tables without registration. Open dataset Open access