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Open datasets · 82 records

Open datasets

Public and credentialed-access datasets for research and machine learning: EHR, claims, imaging, genomics, surveys and registries.

SHOWING 82 OF 82 RECORDS
HDB-0001

MIMIC-IV

MIT Laboratory for Computational Physiology De-identified electronic health records from patients admitted to Beth Israel Deaconess Medical Center, covering ICU and emergency department stays from 2008 onward. The de facto standard dataset for clinical machine learning research, with vitals, labs, medications, procedures and linked clinical notes modules. Open dataset Credentialed HDB-0002

eICU Collaborative Research Database

MIT LCP / Philips Healthcare Multi-center ICU database from the Philips eICU telehealth program, covering 200,000+ admissions across hospitals in the United States. Complements MIMIC with multi-center generalizability for critical care research. Open dataset Credentialed HDB-0003

NHANES

CDC / National Center for Health Statistics The National Health and Nutrition Examination Survey combines interviews, physical examinations and laboratory tests on a representative sample of the US population, released in continuous two-year cycles since 1999. A workhorse dataset for epidemiology and public health research. Open dataset Open access HDB-0004

SEER Cancer Registry

National Cancer Institute The Surveillance, Epidemiology, and End Results program collects cancer incidence, treatment and survival data from population-based registries covering roughly half of the US population. The reference source for US cancer statistics. Open dataset By application HDB-0005

UK Biobank

UK Biobank Ltd Deep genetic, imaging and health data from 500,000 UK participants, linked to national health records with ongoing follow-up. The most-used large-scale biobank in the world for genomic and precision-medicine research; access requires an approved application and access fee. Open dataset By application HDB-0006

All of Us Research Program

National Institutes of Health NIH's flagship precision-medicine cohort, enrolling a diverse US population with surveys, EHR data, genomics and wearable data. Researchers work in a cloud-based Researcher Workbench with tiered access levels. Open dataset Credentialed HDB-0007

HCUP Databases

Agency for Healthcare Research and Quality The Healthcare Cost and Utilization Project family of databases (including the National Inpatient Sample) captures hospital inpatient, emergency and ambulatory encounters across the US. The standard source for hospital utilization, cost and outcomes research; datasets are purchased with a data use agreement. Open dataset Paid HDB-0008

openFDA

US Food and Drug Administration Open APIs and bulk downloads for FDA regulatory data: drug adverse events (FAERS), drug labels, recalls, device reports and more. Free, well-documented JSON APIs that power pharmacovigilance and regulatory analytics tools. Open dataset Open access HDB-0009

NPPES NPI Registry

Centers for Medicare & Medicaid Services The public registry of every US healthcare provider and organization with a National Provider Identifier, searchable via API and downloadable as monthly bulk files. The foundation layer for US provider directories and healthcare B2B data products. Open dataset Open access HDB-0010

WHO Global Health Observatory

World Health Organization The WHO's repository of health indicators for its member states: mortality, disease burden, health systems, environmental health and more, with an open OData API. The starting point for cross-country health comparisons. Open dataset Open access HDB-0038

Europe PMC

EMBL-EBI Open biomedical literature repository developed by EMBL-EBI containing 48+ million articles, preprints, books, and theses from global sources. Freely accessible to anyone worldwide with REST APIs and bulk download capabilities; supported by 35 international research funders as an ELIXIR core data resource. Open dataset Open access HDB-0040

dbGaP (Database of Genotype and Phenotype)

National Center for Biotechnology Information (NCBI), National Institutes of Health dbGaP is a repository of genotype and phenotype data from human research studies, maintained by the National Center for Biotechnology Information (NCBI) at the National Institutes of Health. The database contains data from over 3,400 studies with over 8 million participants, with some data publicly available and other datasets requiring formal access authorization. Open dataset Open access HDB-0041

Gene Expression Omnibus (GEO)

National Center for Biotechnology Information (NCBI), National Institutes of Health The Gene Expression Omnibus is a public repository for gene expression and epigenomics data from microarray and sequencing experiments, operated by NCBI. It houses over 292,000 studies and 8.6 million samples, which researchers can search, download, and analyze through web-based tools or programmatic interfaces. Open dataset Open access HDB-0042

TCGA via NCI Genomic Data Commons

National Cancer Institute (NCI), National Institutes of Health The NCI Genomic Data Commons is a repository and analysis platform for cancer genomics data, including data from The Cancer Genome Atlas (TCGA), which characterized over 20,000 cancer samples across 33 cancer types. Data is accessed through the GDC web portal, API, or data transfer tools, with controlled-access datasets requiring authorization. Open dataset Open access HDB-0043

gnomAD (Genome Aggregation Database)

Broad Institute, Collaborators The Genome Aggregation Database is a resource of aggregated exome and whole-genome sequencing data containing over 241 million genetic variants from over 141,000 diverse individuals, curated by the Broad Institute and collaborators. Summary data are freely available without restrictions through the gnomAD browser, cloud storage, and programmatic interfaces. Open dataset Open access HDB-0044

IGSR / 1000 Genomes Project

European Molecular Biology Laboratory (EMBL), European Bioinformatics Institute The International Genome Sample Resource maintains human genetic variation data from the 1000 Genomes Project, including updated reference assemblies and new datasets, operated by EMBL-EBI. All data are openly accessible through the IGSR portal with searchable filtering tools for accessing samples by population and sequencing method. Open dataset Open access HDB-0045

ClinVar

National Center for Biotechnology Information (NCBI), National Institutes of Health ClinVar is a public archive of human genetic variants and their clinical significance, maintained by NCBI and aggregating submissions from over 3,400 submitters worldwide. Researchers can search, download, and programmatically access information about millions of variants and their relationships to diseases and drug responses. Open dataset Open access HDB-0046

GTEx Portal

Broad Institute, National Institutes of Health The Genotype-Tissue Expression Portal provides tissue-specific gene expression and quantitative trait locus (QTL) data from 54 non-diseased tissue sites across approximately 1,000 individuals, maintained by the Broad Institute with NIH support. Data including raw RNA-seq reads, processed expression matrices, and QTL results are freely accessible through the portal's web interface and API. Open dataset Open access HDB-0047

ArrayExpress (BioStudies)

European Molecular Biology Laboratory (EMBL), European Bioinformatics Institute ArrayExpress is a repository for functional genomics experiments including array and sequence-based studies, housed within the BioStudies database at EMBL-EBI. Researchers can browse, submit, and download experimental metadata, protocols, and data files through web interfaces or specialized tools like the Bioconductor package and Annotare submission system. Open dataset Open access HDB-0048

The Cancer Imaging Archive (TCIA)

National Cancer Institute (NCI) TCIA is a service that de-identifies and hosts large archives of medical images of cancer accessible for public download. The archive contains cancer-related imaging collections organized by disease type, imaging modality, and research focus, supporting research in radiology image analysis. Open dataset Open access HDB-0049

NIH ChestX-ray14

NIH Clinical Center NIH ChestX-ray14 is a publicly available dataset of 112,120 de-identified frontal-view chest radiographs from 30,805 patients, each labeled with 14 thoracic diseases via natural language processing of radiological reports. The dataset serves as a benchmark for developing and evaluating deep learning models for automated chest X-ray interpretation. Open dataset Open access HDB-0050

CheXpert

Stanford ML Group CheXpert is a large dataset comprising 224,316 chest radiographs from 65,240 patients collected from Stanford Hospital, with labels for 14 clinical observations extracted from radiology reports. The dataset is designed for developing and benchmarking algorithms for automated chest radiograph interpretation. Open dataset Free registration HDB-0051

MIMIC-CXR

MIT Laboratory for Computational Physiology MIMIC-CXR is a publicly available dataset of 377,110 chest X-ray images in DICOM and JPEG formats corresponding to 227,835 radiographic studies from Beth Israel Deaconess Medical Center, each paired with free-text radiology reports. Access requires credentialing and completion of research training to comply with HIPAA privacy protections. Open dataset Credentialed HDB-0052

ADNI (Alzheimer's Disease Neuroimaging Initiative)

National Institute on Aging (NIA) ADNI is a longitudinal, multi-center study of Alzheimer's disease featuring data from over 2,500 participants across the United States and Canada, including neuroimaging (MRI, PET), biomarkers, genetic data, and cognitive assessments. The initiative aims to develop and validate biomarkers for early detection and tracking of Alzheimer's disease progression. Open dataset Free registration HDB-0053

OASIS Brains

Washington University School of Medicine OASIS is a project providing four open-access collections of neuroimaging data from over 1,500 subjects spanning lifespan and disease states including normal aging and Alzheimer's disease. The datasets include multiple modalities (T1/T2-weighted MRI, FLAIR, PET) and longitudinal follow-up data from individual subjects. Open dataset Free registration HDB-0054

ISIC Archive

International Skin Imaging Collaboration The ISIC Archive is a large open-source repository containing approximately 549,571 dermatological images of skin lesions including melanomas, nevi, and other skin conditions, with clinical and histological metadata. The archive supports algorithm development for melanoma detection and dermatological diagnosis through curated datasets and annual machine learning challenges. Open dataset Open access HDB-0055

OpenNeuro

Stanford Center for Reproducible Neuroscience OpenNeuro is a free, open-access repository for sharing human and non-human brain imaging data in standardized Brain Imaging Data Structure (BIDS) format, hosting over 600 datasets across multiple modalities including fMRI, structural MRI, EEG, MEG, and PET. Each dataset receives a persistent DOI and is released under Creative Commons CC0 license for maximum data reuse. Open dataset Open access HDB-0056

CMS Data Portal

Centers for Medicare & Medicaid Services (CMS) The CMS Data Portal provides access to administrative claims data, enrollment records, and quality measures for over 160 million Americans covered by Medicare, Medicaid, CHIP, and the Health Insurance Marketplace. Data is available through Public Use Files (free, de-identified) and Research Identifiable Files (restricted access requiring formal application). Open dataset Free registration HDB-0057

CMS Open Payments

Centers for Medicare & Medicaid Services (CMS) Open Payments is a transparency program that tracks financial relationships between pharmaceutical, device, and medical supply manufacturers and physicians and hospitals. The database publishes annually on or by June 30 and includes general payments, research payments, and ownership or investment interests. Open dataset Open access HDB-0058

HealthData.gov

U.S. Department of Health and Human Services (HHS) HealthData.gov is an HHS data portal providing thousands of downloadable health-related datasets from across HHS agencies including health indicators, healthcare quality metrics, inpatient data, and geographic health information. The platform includes a searchable catalog, analytics dashboards, data stories, and APIs for programmatic access. Open dataset Open access HDB-0059

CDC WONDER

Centers for Disease Control and Prevention (CDC), National Center for Health Statistics (NCHS) CDC WONDER (Wide-ranging Online Data for Epidemiologic Research) is an online query system providing access to public health surveillance data including mortality, cancer incidence, HIV/AIDS, tuberculosis, vaccinations, births, and other disease and health event data. Users query county-level and state-level data through fill-in-the-blank web forms with dynamically calculated statistics, charts, and maps. Open dataset Open access HDB-0060

BRFSS (Behavioral Risk Factor Surveillance System)

Centers for Disease Control and Prevention (CDC) BRFSS is a continuous telephone survey system conducted in all 50 states, DC, and three territories that collects state-level data on health-related risk behaviors, chronic health conditions, and preventive service use among U.S. adults. Data from over 400,000 annual interviews are made publicly available through the CDC website and CDC WONDER database. Open dataset Open access HDB-0061

County Health Rankings & Roadmaps

University of Wisconsin Population Health Institute (UWPHI) in partnership with Robert Wood Johnson Foundation County Health Rankings & Roadmaps provides annual county-level health data for nearly every U.S. county measuring health outcomes and health factors including mortality, chronic disease, employment, food access, air and water quality, education, and lifestyle behaviors. Data is accessible through an interactive online portal organized by state and county with downloadable datasets and evidence-based improvement strategies. Open dataset Open access HDB-0062

VAERS (Vaccine Adverse Event Reporting System)

Centers for Disease Control and Prevention (CDC) and Food and Drug Administration (FDA) VAERS is a post-licensure vaccine safety surveillance system jointly administered by CDC and FDA that collects and analyzes reports of adverse events following vaccination from healthcare providers, manufacturers, and the public. The system publishes data through downloadable datasets and an online search interface integrated with CDC WONDER for detecting unusual or unexpected patterns in adverse events. Open dataset Open access HDB-0063

Medicare Part D Prescriber Data

Centers for Medicare & Medicaid Services (CMS) This CMS dataset contains the number of prescription fills and total drug costs paid organized by prescribing National Provider Identifier (NPI), drug brand name, and drug generic name for medications prescribed to Medicare Part D beneficiaries. The dataset is updated annually and is based on CMS administrative claims data from the Chronic Condition Data Warehouse. Open dataset Open access HDB-0064

OECD Health Statistics

Organisation for Economic Co-operation and Development (OECD) OECD Health Statistics is a comprehensive database of health and health systems data maintained by the OECD, covering 35+ member countries. It provides comparable statistics on health expenditure, resources, services utilization, and key health indicators for policy analysis and research. Open dataset Open access HDB-0065

Eurostat Health Database

Eurostat (European Commission) Eurostat's health database provides statistical information on health and health systems across EU member states and associated countries. It covers health expenditure, resources, activities, and services with data structured by topic and accessible through interactive tools and bulk download. Open dataset Open access HDB-0066

IHME Global Health Data Exchange (GHDx)

Institute for Health Metrics and Evaluation (IHME) The Global Health Data Exchange (GHDx) is IHME's catalog of health and demographic data, including estimates from the Global Burden of Disease study assessing mortality and disability from diseases and injuries globally. Access requires free registration and is available for non-commercial use under IHME's free-of-charge agreement. Open dataset Free registration HDB-0067

Human Mortality Database

UC Berkeley & Max Planck Institute for Demographic Research The Human Mortality Database (HMD) is a joint project providing detailed harmonized mortality and population data for 41 developed countries and regions. Data is openly available under open data principles and can be downloaded as files or accessed through country-specific interfaces and Excel tables. Open dataset Open access HDB-0068

The DHS Program

USAID / Avenir Health The DHS Program is a USAID-funded effort that conducts Demographic and Health Surveys across 90+ countries to collect data on population, health, and nutrition. Survey data is available free for academic research through the STATcompiler tool and downloadable datasets with free registration. Open dataset Free registration HDB-0069

Our World in Data - Health

University of Oxford (Oxford Martin Programme on Global Development) Our World in Data maintains a collection of global health datasets including life expectancy, disease burden, healthcare spending, and disease prevalence, drawn from WHO, World Bank, IHME, and UN agencies. Data is presented through interactive visualizations available under Creative Commons licensing. Open dataset Open access HDB-0070

CBS StatLine Health

CBS (Centraal Bureau voor de Statistiek - Statistics Netherlands) CBS StatLine is the electronic database of Statistics Netherlands providing open access to official Dutch statistics on health and welfare topics. Users can create custom tables and download health data at no cost; microdata access requires authorization. Open dataset Open access HDB-0071

Vektis Open Data

Vektis (Dutch healthcare information organization) Vektis manages healthcare cost data from the Dutch Health Insurance Act, providing aggregated open datasets on healthcare spending by service type at postal code and municipal levels. Data is freely downloadable as CSV files with annual updates covering 2011-2024. Open dataset Open access HDB-0080

INDEPTH Network Health and Demographic Surveillance Systems (HDSS)

International Network for the Demographic Evaluation of Populations and Their Health (INDEPTH) INDEPTH operates 47 health and demographic surveillance system (HDSS) field sites across 19 countries in Africa, Asia, and Oceania, capturing longitudinal data on vital events and population health for over 3.8 million individuals. The network provides access to fully documented datasets through its data repository (data.indepth-network.org), enabling research on mortality, fertility, migration, and disease patterns in low- and middle-income countries. Open dataset Credentialed HDB-0081

South Africa National Health Laboratory Service (NHLS)

National Health Laboratory Service The NHLS is a South African national public entity providing diagnostic pathology services and laboratory testing to over 80% of the South African population through a countrywide network of quality-assured laboratories. The organization operates LabTrack (a laboratory test tracking system) and maintains the National HIV Cohort, generating surveillance data on diagnostic patterns and HIV treatment outcomes across the country. Open dataset Credentialed HDB-0083

African Population and Health Research Center (APHRC) Microdata Portal

African Population and Health Research Center APHRC's microdata portal provides access to 134+ documented datasets from research studies conducted across African countries, particularly Kenya, with detailed metadata on study design, sampling procedures, and data dictionaries. The portal hosts data from the Nairobi Urban Health and Demographic Surveillance System (NUHDSS) and numerous longitudinal studies on population, health, and education issues in sub-Saharan Africa. Open dataset Free registration HDB-0084

Human Heredity and Health in Africa (H3Africa)

H3Africa Consortium (NIH, Wellcome Trust, Science for Africa Foundation) H3Africa is a consortium-based initiative funded by the U.S. National Institutes of Health and the Wellcome Trust that conducts genomic research on the health determinants of common diseases across multiple African populations. The initiative manages 51 active research projects generating large-scale genomic and environmental data with documented governance through a Data and Biospecimen Access Committee. Open dataset Credentialed HDB-0085

Africa CDC Health Knowledge Hub

Africa Centres for Disease Control and Prevention (Africa CDC) The Africa CDC Health Knowledge Hub serves as the central platform for disease surveillance, outbreak tracking, and health emergency data across the African continent under the African Union. The hub provides real-time disease outbreak information, health publications, and surveillance data integrated through Africa CDC's recently established Central Data Repository using a federated model. Open dataset Open access HDB-0087

WHO AFRO Integrated African Health Observatory (iAHO)

World Health Organization Regional Office for Africa (WHO AFRO) The integrated African Health Observatory (iAHO) is the strategic health intelligence platform hosting health data, analytics, and evidence for the WHO African Region encompassing 47 Member States and their National Health Observatories. The platform marshals standardized health data, performs in-depth analysis, and disseminates key health information for policy dialogue and health decision-making. Open dataset Open access HDB-0088

China Kadoorie Biobank

University of Oxford Clinical Trial Service Unit & Chinese Academy of Medical Sciences A prospective cohort biobank collecting blood samples, questionnaire data, and clinical information from over 510,000 Chinese adults aged 30-79 recruited between 2004-2008 from 10 regions. The resource enables investigation of genetic and environmental factors in chronic disease etiology through long-term follow-up and research collaborations. Open dataset Credentialed HDB-0089

BioBank Japan

Institute of Medical Science, University of Tokyo A disease-focused biobank established in 2003 maintaining DNA and serum samples from approximately 270,000 patients with 51 targeted diseases, with whole genome sequencing available for over 16,000 participants. The resource supports personalized medicine research with findings published in major scientific journals. Open dataset Credentialed HDB-0091

Korea National Health and Nutrition Examination Survey (KNHANES)

Korea Disease Control and Prevention Agency (KDCA) An annual national surveillance survey conducted since 1998 examining the health and nutritional status of approximately 10,000 representative Korean individuals. The survey collects data on socioeconomic factors, health behaviors, clinical/biochemical profiles, and dietary intake to inform national health policy development. Open dataset Open access HDB-0094

China Health and Retirement Longitudinal Study (CHARLS)

Peking University National School of Development & Institute of Social Science Survey A nationally representative longitudinal survey tracking health, retirement, and socioeconomic data for Chinese residents aged 45 and older, with baseline sample of over 17,000 individuals from 150 counties. The biennial survey (baseline 2011-2012, latest Wave 5 in 2020) includes physical measurements, cognitive assessments, and biomarkers comparable to international aging cohorts. Open dataset Free registration HDB-0096

National Family Health Survey (NFHS)

International Institute for Population Sciences (IIPS), Ministry of Health and Family Welfare Large-scale multi-round national household survey conducted across India since 1992-93, providing data on fertility, mortality, family planning, maternal and child health, nutrition, and reproductive health. Data is publicly accessible through factsheets and datasets organized by survey round and state. Open dataset Open access HDB-0099

Longitudinal Ageing Study in India (LASI)

International Institute for Population Sciences (IIPS), in collaboration with National Institute on Aging (USA) and Harvard School of Public Health India's first and largest longitudinal study of ageing, tracking over 73,000 adults aged 45 and older across all states and union territories to assess health, economic, social, and wellbeing dimensions. Wave 1 was conducted in 2017-18, with Wave 2 scheduled for 2024-25; data supports research on aging and policy development. Open dataset Free registration HDB-0100

Indonesian Family Life Survey (IFLS)

RAND Corporation Longitudinal household survey begun in 1993, representing 83 percent of Indonesia's population with detailed data on over 30,000 individuals across 13 provinces. Data covers consumption, income, assets, education, migration, labor, fertility, contraceptive use, health status, health insurance, and family relationships; researchers must register to access public-use data files. Open dataset Free registration HDB-0101

Health Information System Development Office (HISO) - Thailand Health Data Portal

Health Information System Development Office (HISO), Ministry of Public Health, Thailand Thailand's centralized health information and statistics portal that collects health data from domestic organizations including the Ministry of Public Health, National Statistical Office, National Health Security Office, and international agencies. Portal provides access to health indicators, statistics, reports, and visualization tools for trend analysis. Open dataset Open access HDB-0103

Malaysia National Health and Morbidity Survey (NHMS)

Institute for Public Health (IKU), National Institutes of Health, Ministry of Health Malaysia Annual national cross-sectional household health survey conducted by Malaysia's Ministry of Health since 2011 to monitor population health status and health-related behaviors. Each annual survey focuses on specific health themes and provides state-level and national data to support health policy-making and service planning. Open dataset Open access HDB-0104

Philippines National Demographic and Health Survey (NDHS)

Philippine Statistics Authority (PSA) in collaboration with DHS Program Nationally-representative survey conducted by the Philippine Statistics Authority (now every 3 years, previously every 5 years) as part of the global DHS program, tracking population dynamics, fertility, family planning, maternal and child health, nutrition, and health service utilization. The 2022 NDHS was the seventh DHS conducted in the Philippines since 1968. Open dataset Open access HDB-0106

Qatar Precision Health Institute

Qatar Foundation The Qatar Precision Health Institute maintains large-scale genomic and biobank repositories of biological samples and health data from Qatari citizens and residents, including whole genome sequencing data and a disease genomics database. The institute provides research access through a research portal and offers customized genotyping tools including the Q-Chip microarray developed from genomic data. Open dataset Credentialed HDB-0110

Emirati Reference Genome Programme

Department of Health, Abu Dhabi; Group 42 The Emirati Reference Genome Programme is a national genomics initiative launched in 2021 that collects biological samples and generates whole-genome sequencing data from Emirati citizens to create a reference genome representing the genetic diversity of the UAE population. The programme combines advanced sequencing technology and artificial intelligence to develop precision medicine applications tailored to Emirati genetics and support discovery of population-specific disease variants. Open dataset Credentialed HDB-0111

Turkish Statistical Institute (TUIK) Health Statistics Portal

Turkish Statistical Institute (TUIK) The Turkish Statistical Institute maintains a comprehensive health statistics portal with aggregated data on Turkey's population health including mortality, morbidity, health expenditure, disability, and healthcare utilization statistics. The portal provides public access to downloadable datasets and indicators covering health and social protection statistics compiled from national health surveillance systems. Open dataset Open access HDB-0139

DATASUS

Ministry of Health (Ministério da Saúde), Brazil DATASUS is Brazil's integrated health information system operated by the Department of Information Technology, providing data from the Unified Health System (SUS) including hospital admissions, outpatient services, mortality, births, notifiable diseases, and health establishments. The platform offers public access to health data through multiple tools including TABNET for analysis, RNDS for interoperable data sharing, and administrative dashboards covering all Brazilian municipalities and states. Open dataset Open access HDB-0140

SISA

Ministry of Health (Ministerio de Salud de la Nación), Argentina SISA (Sistema Integrado de Información Sanitaria Argentino) is Argentina's integrated health information system that consolidates federal health registries including health establishments, licensed professionals, and real-time epidemiological surveillance data. The platform integrates multiple registries (REFES, REFEPS, SNVS 2.0) with a federal network architecture linking healthcare services, provincial agencies, and the national Ministry of Health. Open dataset Free registration HDB-0141

PAHO/EIH Open Data

Pan American Health Organization (PAHO/WHO) PAHO/EIH Open Data (formerly PLISA) is a regional health information platform providing over 140 health indicators covering countries and territories across the Americas since 1995. The platform includes disease incidence and mortality data, vaccination coverage, outbreak information, non-communicable disease indicators, mental health data, and environmental health determinants disaggregated by age, sex, and urban-rural distribution. Open dataset Open access HDB-0142

Australian Institute of Health and Welfare (AIHW) Data Collections

Australian Institute of Health and Welfare AIHW maintains over 150 datasets covering health and welfare topics including perinatal health, disability, cancer, hospital activity, alcohol and drug use, and mortality collected from Australian healthcare services. Researchers access linked data through AIHW's data linkage services, which combine administrative health records with survey and registry data. Open dataset Credentialed HDB-0159

N3C (National COVID Cohort Collaborative)

NIH NCATS (National Center for Advancing Translational Sciences) N3C is a centralized research platform that aggregates de-identified electronic health record data from over 90 institutions into a secure enclave, containing data on over 500,000 patients for COVID-19, Long COVID, and other disease research. Registered researchers can access the data to conduct collaborative studies on multiple disease domains with full data provenance documentation and strong privacy protections. Open dataset Free registration HDB-0162

Framingham Heart Study

Boston University School of Medicine, National Heart, Lung, and Blood Institute (NHLBI) A prospective cohort study that began in 1948 and now includes three generations with more than 15,000 participants and over 2 million biosamples collected over 78 years. Researchers access data through a formal application process via the Research Application Portal, with datasets available for cardiovascular disease, brain aging, metabolism, and genetics. Open dataset By application HDB-0163

ALSPAC (Avon Longitudinal Study of Parents and Children)

University of Bristol A birth cohort study that recruited over 14,000 pregnant women between 1991-1992 and has continuously monitored participants and their descendants. Researchers can access study data by submitting research proposals through the dedicated proposal portal, with datasets available from longitudinal assessments, cognitive testing, and a new cohort of grandchildren. Open dataset By application HDB-0164

SHARE (Survey of Health, Ageing and Retirement in Europe)

SHARE-ERIC (European Research Infrastructure Consortium) Europe's largest social science panel study collecting longitudinal data on health, biomarkers, employment, cognition, and economics across 28 participating countries. Researchers register as users and access data through the dedicated data portal (share-project.org/data), with approximately 690,000 interviews from 175,000 respondents supporting over 4,800 publications. Open dataset Free registration HDB-0165

ELSA (English Longitudinal Study of Ageing)

NatCen Social Research in partnership with University College London and Institute for Fiscal Studies A longitudinal study of English aging spanning 24 years across 11 waves of data collection involving 24,000+ participants. Researchers can download datasets directly from the website, with additional procedures for accessing genetic data, supported by comprehensive user guides and the contact point ELSAdata@natcen.ac.uk. Open dataset Open access HDB-0166

Lifelines (Dutch Biobank and Cohort Study)

Lifelines Biobank, University Medical Center Groningen The Netherlands' largest biobank with over 167,000 participants providing health data and biological samples approximately every five years. Researchers submit data access applications through the dedicated biobank portal (lifelines-biobank.com), gaining access to well-organized questionnaires and datasets supporting over 750 scientific publications. Open dataset By application HDB-0167

Millennium Cohort Study (MCS)

Centre for Longitudinal Studies (CLS), University College London A birth cohort study following approximately 19,000 young people born in 2000-2002 across England, Scotland, Wales, and Northern Ireland through their life course. Researchers access data through CLS's data access portal with resources including documentation, a bibliography of 6,000+ publications, and training webinars, with a new consolidated core dataset released in July 2026. Open dataset Free registration HDB-0168

German National Cohort Study (NAKO)

German Federal Ministry of Education and Research and participating research institutions Germany's largest long-term study researching common diseases with participants undergoing ongoing examinations and health questionnaires in multiple phases. Researchers can access information through the NAKO TransferHub and contact research-responsible persons for collaboration, with resources supporting multiple research projects and an International NAKO Conference planned for 2026. Open dataset By application HDB-0169

WHO Data Platform

World Health Organization The WHO Data Platform (data.who.int) is a centralized interactive digital portal providing access to trusted global health data and statistics across thousands of health indicators. The platform offers browsable data by country and indicator, downloadable datasets, interactive visualizations tracking Triple Billion targets and health emergencies, and country-level health profiles. Open dataset Open access HDB-0170

WHO Global Health Expenditure Database (National Health Accounts)

World Health Organization The WHO Global Health Expenditure Database provides comparable health spending data for 195 countries and territories since 2000, including breakdowns by funding sources, financing arrangements, health functions, and disease-specific expenditures. The database is updated annually and tracks capital investments and country-level health expenditure profiles. Open dataset Open access HDB-0171

World Bank Health, Nutrition and Population Statistics

World Bank The World Bank provides comprehensive health, nutrition, and population statistics through its DataBank platform, offering over 50 health-related indicators including mortality rates, life expectancy, disease prevalence, immunization rates, and nutritional status measures. Data covers 195 countries with downloadable formats in CSV, XML, and Excel. Open dataset Open access HDB-0172

UNAIDS AIDSinfo

UNAIDS UNAIDS AIDSinfo provides comprehensive HIV/AIDS epidemiological estimates, country-reported data on national AIDS responses, service coverage metrics, and financial resource tracking with over 85 indicators on HIV funding. The platform includes data on key populations, HIV-related policies and legal frameworks, and health inequalities in HIV progress. Open dataset Open access HDB-0173

Global Fund Data Explorer

The Global Fund to Fight AIDS, Tuberculosis and Malaria The Global Fund Data Explorer provides public access to performance metrics and results data related to AIDS, tuberculosis, and malaria programs funded through the Global Fund. The platform enables stakeholders and the public to track grant performance, funding allocation, and programmatic outcomes. Open dataset Open access HDB-0174

Gapminder Health Datasets

Gapminder Foundation Gapminder provides free interactive data visualization tools and datasets on global health, demographics, and development indicators sourced from the UN and other reliable international sources. The platform offers animated datasets and visualization tools to examine health trends and misconceptions about global health progress. Open dataset Open access HDB-0176

MedMNIST

Jiancheng Yang et al. A collection of 18 standardized medical imaging datasets (12 2D and 6 3D) spanning multiple modalities including pathology, retinal imaging, breast ultrasound, and chest radiography. Datasets are pre-processed and curated for machine learning benchmarking with consistent train-validation-test splits. Open dataset Open access HDB-0177

CAMELYON17

Diagnostic Image Analysis Group (DIAG), Radboud University Medical Center; Department of Pathology, Leiden University Medical Center An open-access histopathology dataset of 1,399 H&E-stained whole-slide images of sentinel lymph nodes from breast cancer patients, created for automated detection and classification of metastases. The dataset includes training and test sets with pixel-level annotations. Open dataset Open access