Health databases & datasets: US

HDB-0001

MIMIC-IV

MIT Laboratory for Computational Physiology De-identified electronic health records from patients admitted to Beth Israel Deaconess Medical Center, covering ICU and emergency department stays from 2008 onward. The de facto standard dataset for clinical machine learning research, with vitals, labs, medications, procedures and linked clinical notes modules. Open dataset Credentialed HDB-0002

eICU Collaborative Research Database

MIT LCP / Philips Healthcare Multi-center ICU database from the Philips eICU telehealth program, covering 200,000+ admissions across hospitals in the United States. Complements MIMIC with multi-center generalizability for critical care research. Open dataset Credentialed HDB-0003

NHANES

CDC / National Center for Health Statistics The National Health and Nutrition Examination Survey combines interviews, physical examinations and laboratory tests on a representative sample of the US population, released in continuous two-year cycles since 1999. A workhorse dataset for epidemiology and public health research. Open dataset Open access HDB-0004

SEER Cancer Registry

National Cancer Institute The Surveillance, Epidemiology, and End Results program collects cancer incidence, treatment and survival data from population-based registries covering roughly half of the US population. The reference source for US cancer statistics. Open dataset By application HDB-0006

All of Us Research Program

National Institutes of Health NIH's flagship precision-medicine cohort, enrolling a diverse US population with surveys, EHR data, genomics and wearable data. Researchers work in a cloud-based Researcher Workbench with tiered access levels. Open dataset Credentialed HDB-0007

HCUP Databases

Agency for Healthcare Research and Quality The Healthcare Cost and Utilization Project family of databases (including the National Inpatient Sample) captures hospital inpatient, emergency and ambulatory encounters across the US. The standard source for hospital utilization, cost and outcomes research; datasets are purchased with a data use agreement. Open dataset Paid HDB-0008

openFDA

US Food and Drug Administration Open APIs and bulk downloads for FDA regulatory data: drug adverse events (FAERS), drug labels, recalls, device reports and more. Free, well-documented JSON APIs that power pharmacovigilance and regulatory analytics tools. Open dataset Open access HDB-0009

NPPES NPI Registry

Centers for Medicare & Medicaid Services The public registry of every US healthcare provider and organization with a National Provider Identifier, searchable via API and downloadable as monthly bulk files. The foundation layer for US provider directories and healthcare B2B data products. Open dataset Open access HDB-0013

Definitive Healthcare

Definitive Healthcare, LLC Commercial healthcare intelligence platform profiling US hospitals, health systems, physicians and payers, with affiliations, technology installs, claims-based volumes and executive contacts. Widely used by sales, marketing and strategy teams selling into healthcare. Commercial provider Paid HDB-0015

Ampliz

Ampliz Healthcare-focused B2B contact and intelligence platform covering physicians, executives and facilities in the US, positioned for SMB and mid-market sales teams. Provides verified emails, direct dials and firmographic data with healthcare-specific segmentation. Commercial provider Paid HDB-0016

Komodo Health

Komodo Health Komodo Health operates Healthcare Map, a de-identified patient-level data platform combining linked claims, EHR and outcomes records, refreshed daily. Access requires enterprise contract through direct engagement with Komodo's sales and solutions team. Commercial provider By application HDB-0017

Truveta

Truveta (collaborative health systems) Truveta Data provides daily-updated electronic health records and claims sourced directly from member health systems. Organizations access data through Truveta Evidence (trusted research environment) or Truveta Intelligence (query-based analysis tool), with expert-guided research services available. Commercial provider By application HDB-0018

Optum Life Sciences (Market Clarity / Clinformatics)

Optum (UnitedHealth Group) Optum offers Market Clarity and Clinformatics Data Mart, de-identified repositories containing claims and clinical data with mapped clinical variables and prescription records. Access is provided through licensed commercial agreements with Optum's sales organization. Commercial provider Paid HDB-0019

Merative MarketScan

Merative MarketScan is a proprietary United States claims database containing de-identified commercial and Medicaid insurance claims data supporting real-world evidence research. Academic institutions, pharmaceutical companies, and researchers access the data through Merative's workspace tools and research services, with specialized dissertation support available. Commercial provider By application HDB-0020

HealthVerity

HealthVerity HealthVerity Marketplace aggregates de-identified healthcare data from multiple sources, including claims, EHR, labs, pharmacy, consumer data, and social determinants of health. Organizations access datasets through the marketplace via custom licensing agreements with configurable data selection. Commercial provider By application HDB-0021

Datavant

Datavant Datavant's Health Data Nexus consolidates de-identified clinical records, claims, and patient charts into unified longitudinal patient views for healthcare organizations. Payers and providers access structured and enriched data through the cloud-based platform for applications including risk adjustment, quality programs, and population health analytics. Commercial provider By application HDB-0022

Clarify Health

Clarify Health Solutions Clarify Health's Atlas Platform provides a database of longitudinal records, negotiated pricing rates, and machine learning-trained outcomes predictions. Health systems and payers access the data through the Meridian product for referral network optimization and care pathway analytics. Commercial provider By application HDB-0023

Symphony Health (ICON)

Symphony Health (ICON plc / HealthVerity) Symphony Health's Integrated Dataverse provides de-identified medical, hospital, prescription, and demographic claims data linked at the patient level. The platform is now integrated into HealthVerity's broader ecosystem, offering access to specialty data products and analytics through the HealthVerity Marketplace. Commercial provider By application HDB-0027

Doximity

Doximity Inc. Doximity is a professional network for U.S. healthcare clinicians, operated by Doximity Inc., with over 3 million members including more than 85% of U.S. physicians plus nurses, pharmacists, and other healthcare professionals. The platform provides a professional directory, secure messaging, and clinical communication services; registration and use are free for verified U.S. healthcare professionals, with additional enterprise services available to healthcare organizations. Commercial provider Free registration HDB-0028

CarePrecise

CarePrecise CarePrecise is a U.S. healthcare provider database containing information on more than 9.3 million providers, including physicians, dentists, pharmacists, nurses, hospitals, and clinics, compiled from CMS, federal, and other authoritative sources. The platform serves researchers, healthcare organizations, and commercial entities for workforce analysis and provider outreach through paid subscription packages with varying data comprehensiveness. Commercial provider Paid HDB-0040

dbGaP (Database of Genotype and Phenotype)

National Center for Biotechnology Information (NCBI), National Institutes of Health dbGaP is a repository of genotype and phenotype data from human research studies, maintained by the National Center for Biotechnology Information (NCBI) at the National Institutes of Health. The database contains data from over 3,400 studies with over 8 million participants, with some data publicly available and other datasets requiring formal access authorization. Open dataset Open access HDB-0041

Gene Expression Omnibus (GEO)

National Center for Biotechnology Information (NCBI), National Institutes of Health The Gene Expression Omnibus is a public repository for gene expression and epigenomics data from microarray and sequencing experiments, operated by NCBI. It houses over 292,000 studies and 8.6 million samples, which researchers can search, download, and analyze through web-based tools or programmatic interfaces. Open dataset Open access HDB-0042

TCGA via NCI Genomic Data Commons

National Cancer Institute (NCI), National Institutes of Health The NCI Genomic Data Commons is a repository and analysis platform for cancer genomics data, including data from The Cancer Genome Atlas (TCGA), which characterized over 20,000 cancer samples across 33 cancer types. Data is accessed through the GDC web portal, API, or data transfer tools, with controlled-access datasets requiring authorization. Open dataset Open access HDB-0045

ClinVar

National Center for Biotechnology Information (NCBI), National Institutes of Health ClinVar is a public archive of human genetic variants and their clinical significance, maintained by NCBI and aggregating submissions from over 3,400 submitters worldwide. Researchers can search, download, and programmatically access information about millions of variants and their relationships to diseases and drug responses. Open dataset Open access HDB-0046

GTEx Portal

Broad Institute, National Institutes of Health The Genotype-Tissue Expression Portal provides tissue-specific gene expression and quantitative trait locus (QTL) data from 54 non-diseased tissue sites across approximately 1,000 individuals, maintained by the Broad Institute with NIH support. Data including raw RNA-seq reads, processed expression matrices, and QTL results are freely accessible through the portal's web interface and API. Open dataset Open access HDB-0048

The Cancer Imaging Archive (TCIA)

National Cancer Institute (NCI) TCIA is a service that de-identifies and hosts large archives of medical images of cancer accessible for public download. The archive contains cancer-related imaging collections organized by disease type, imaging modality, and research focus, supporting research in radiology image analysis. Open dataset Open access HDB-0049

NIH ChestX-ray14

NIH Clinical Center NIH ChestX-ray14 is a publicly available dataset of 112,120 de-identified frontal-view chest radiographs from 30,805 patients, each labeled with 14 thoracic diseases via natural language processing of radiological reports. The dataset serves as a benchmark for developing and evaluating deep learning models for automated chest X-ray interpretation. Open dataset Open access HDB-0050

CheXpert

Stanford ML Group CheXpert is a large dataset comprising 224,316 chest radiographs from 65,240 patients collected from Stanford Hospital, with labels for 14 clinical observations extracted from radiology reports. The dataset is designed for developing and benchmarking algorithms for automated chest radiograph interpretation. Open dataset Free registration HDB-0051

MIMIC-CXR

MIT Laboratory for Computational Physiology MIMIC-CXR is a publicly available dataset of 377,110 chest X-ray images in DICOM and JPEG formats corresponding to 227,835 radiographic studies from Beth Israel Deaconess Medical Center, each paired with free-text radiology reports. Access requires credentialing and completion of research training to comply with HIPAA privacy protections. Open dataset Credentialed HDB-0052

ADNI (Alzheimer's Disease Neuroimaging Initiative)

National Institute on Aging (NIA) ADNI is a longitudinal, multi-center study of Alzheimer's disease featuring data from over 2,500 participants across the United States and Canada, including neuroimaging (MRI, PET), biomarkers, genetic data, and cognitive assessments. The initiative aims to develop and validate biomarkers for early detection and tracking of Alzheimer's disease progression. Open dataset Free registration HDB-0053

OASIS Brains

Washington University School of Medicine OASIS is a project providing four open-access collections of neuroimaging data from over 1,500 subjects spanning lifespan and disease states including normal aging and Alzheimer's disease. The datasets include multiple modalities (T1/T2-weighted MRI, FLAIR, PET) and longitudinal follow-up data from individual subjects. Open dataset Free registration HDB-0056

CMS Data Portal

Centers for Medicare & Medicaid Services (CMS) The CMS Data Portal provides access to administrative claims data, enrollment records, and quality measures for over 160 million Americans covered by Medicare, Medicaid, CHIP, and the Health Insurance Marketplace. Data is available through Public Use Files (free, de-identified) and Research Identifiable Files (restricted access requiring formal application). Open dataset Free registration HDB-0057

CMS Open Payments

Centers for Medicare & Medicaid Services (CMS) Open Payments is a transparency program that tracks financial relationships between pharmaceutical, device, and medical supply manufacturers and physicians and hospitals. The database publishes annually on or by June 30 and includes general payments, research payments, and ownership or investment interests. Open dataset Open access HDB-0058

HealthData.gov

U.S. Department of Health and Human Services (HHS) HealthData.gov is an HHS data portal providing thousands of downloadable health-related datasets from across HHS agencies including health indicators, healthcare quality metrics, inpatient data, and geographic health information. The platform includes a searchable catalog, analytics dashboards, data stories, and APIs for programmatic access. Open dataset Open access HDB-0059

CDC WONDER

Centers for Disease Control and Prevention (CDC), National Center for Health Statistics (NCHS) CDC WONDER (Wide-ranging Online Data for Epidemiologic Research) is an online query system providing access to public health surveillance data including mortality, cancer incidence, HIV/AIDS, tuberculosis, vaccinations, births, and other disease and health event data. Users query county-level and state-level data through fill-in-the-blank web forms with dynamically calculated statistics, charts, and maps. Open dataset Open access HDB-0060

BRFSS (Behavioral Risk Factor Surveillance System)

Centers for Disease Control and Prevention (CDC) BRFSS is a continuous telephone survey system conducted in all 50 states, DC, and three territories that collects state-level data on health-related risk behaviors, chronic health conditions, and preventive service use among U.S. adults. Data from over 400,000 annual interviews are made publicly available through the CDC website and CDC WONDER database. Open dataset Open access HDB-0061

County Health Rankings & Roadmaps

University of Wisconsin Population Health Institute (UWPHI) in partnership with Robert Wood Johnson Foundation County Health Rankings & Roadmaps provides annual county-level health data for nearly every U.S. county measuring health outcomes and health factors including mortality, chronic disease, employment, food access, air and water quality, education, and lifestyle behaviors. Data is accessible through an interactive online portal organized by state and county with downloadable datasets and evidence-based improvement strategies. Open dataset Open access HDB-0062

VAERS (Vaccine Adverse Event Reporting System)

Centers for Disease Control and Prevention (CDC) and Food and Drug Administration (FDA) VAERS is a post-licensure vaccine safety surveillance system jointly administered by CDC and FDA that collects and analyzes reports of adverse events following vaccination from healthcare providers, manufacturers, and the public. The system publishes data through downloadable datasets and an online search interface integrated with CDC WONDER for detecting unusual or unexpected patterns in adverse events. Open dataset Open access HDB-0063

Medicare Part D Prescriber Data

Centers for Medicare & Medicaid Services (CMS) This CMS dataset contains the number of prescription fills and total drug costs paid organized by prescribing National Provider Identifier (NPI), drug brand name, and drug generic name for medications prescribed to Medicare Part D beneficiaries. The dataset is updated annually and is based on CMS administrative claims data from the Chronic Condition Data Warehouse. Open dataset Open access HDB-0074

RxNorm

National Library of Medicine RxNorm is a normalized naming system for generic and branded clinical drugs maintained by the National Library of Medicine, part of the NIH. It provides normalized drug names and links to drug vocabularies commonly used in pharmacy management and drug interaction systems for semantic interoperation. Terminology Open access HDB-0076

UMLS

National Library of Medicine The Unified Medical Language System (UMLS) is a comprehensive repository of biomedical and health terminologies maintained by the National Library of Medicine, part of the NIH. It integrates over 100 medical vocabularies including SNOMED CT, LOINC, and RxNorm to enable interoperability and cross-referencing between different healthcare coding systems. Terminology Credentialed HDB-0157

FDA Sentinel Initiative

FDA (US Food and Drug Administration) The FDA Sentinel Initiative is a distributed system for evaluating the safety and performance of medical products using real-world data from insurance claims, electronic health records, and patient reports covering approximately 138.7 million members. Data remain with their sources (insurance companies, EHR systems, etc.) and are analyzed through a decentralized model that preserves privacy and data security. Research database By application HDB-0158

PCORnet

PCORI (Patient-Centered Outcomes Research Institute) PCORnet is a national research network funded by PCORI that aggregates health data from diverse clinical settings to enable patient-centered comparative effectiveness research and fast, trustworthy evidence generation. The network provides researchers and healthcare organizations with access to clinical data and research infrastructure while incorporating patient perspectives in research design. Research database By application HDB-0159

N3C (National COVID Cohort Collaborative)

NIH NCATS (National Center for Advancing Translational Sciences) N3C is a centralized research platform that aggregates de-identified electronic health record data from over 90 institutions into a secure enclave, containing data on over 500,000 patients for COVID-19, Long COVID, and other disease research. Registered researchers can access the data to conduct collaborative studies on multiple disease domains with full data provenance documentation and strong privacy protections. Open dataset Free registration HDB-0162

Framingham Heart Study

Boston University School of Medicine, National Heart, Lung, and Blood Institute (NHLBI) A prospective cohort study that began in 1948 and now includes three generations with more than 15,000 participants and over 2 million biosamples collected over 78 years. Researchers access data through a formal application process via the Research Application Portal, with datasets available for cardiovascular disease, brain aging, metabolism, and genetics. Open dataset By application HDB-0307

YODA Project

Yale University The Yale Open Data Access Project is a data intermediary that facilitates access to individual participant data from completed clinical trials contributed by pharmaceutical companies and research institutions. Investigators submit research proposals; approved studies gain access to de-identified patient-level datasets for independent analysis and secondary research. IPD repository By application HDB-0311

NHLBI BioLINCC

National Heart, Lung, and Blood Institute (NIH) BioLINCC is the NIH repository for de-identified individual participant data and biospecimens from NHLBI-funded cardiovascular, pulmonary, blood, and sleep disorder studies. Researchers with institutional IRB approval or exemption may request access to datasets through a formal data-access request and data-use agreement process. IPD repository Credentialed HDB-0312

ImmPort

National Institute of Allergy and Infectious Diseases (NIAID) NIH immunology data repository hosting individual participant data from immunology and allergy clinical trials. Researchers register freely to search and download de-identified datasets, or request access to controlled-access studies through the system. IPD repository Free registration HDB-0313

ITN TrialShare

Immune Tolerance Network (NIAID) Immune Tolerance Network repository holding de-identified individual participant data from 27 clinical trials covering transplantation, autoimmunity, allergy, and type 1 diabetes. Researchers create a free account to access de-identified data, explore studies, and perform exploratory analyses. IPD repository Free registration HDB-0314

NIDDK Central Repository

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NIH repository providing access to de-identified individual participant data from diabetes, digestive disease, and kidney disease clinical trials. Researchers identify relevant studies and submit formal data requests to access de-identified datasets through the portal. IPD repository By application HDB-0315

NIMH Data Archive (NDA)

National Institute of Mental Health (NIMH) NIH repository for mental health and neuroscience research hosting de-identified individual participant data from clinical and observational studies. Researchers submit data access requests and sign a Data Use Certification to obtain de-identified datasets from approved studies. IPD repository By application HDB-0316

NICHD DASH

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) NIH Data and Specimen Hub providing access to de-identified individual participant data from child health and maternal-fetal health clinical and population studies. Researchers apply for access through the controlled-access data request process. IPD repository By application HDB-0317

NCTN/NCORP Data Archive

National Cancer Institute (NCI) The NCTN/NCORP Data Archive holds de-identified individual participant data from published phase 2 and phase 3 trials run by NCI's National Clinical Trials Network and Community Oncology Research Program. Researchers request datasets through the archive's online system, with approval governed by data use agreements. IPD repository By application HDB-0320

NIA Aging Research Biobank

National Institute on Aging (NIA), National Institutes of Health The Aging Research Biobank archives and distributes de-identified participant-level clinical data, imaging data, and biospecimens from completed NIA-funded clinical trials and longitudinal studies, including ASPREE, CALERIE, and the Testosterone Trials. Principal investigators register with identity verification, submit a request for materials with a protocol and IRB documentation, and receive data under a signed transfer agreement after scientific review and NIA approval. IPD repository By application HDB-0321

NIDA Data Share

National Institute on Drug Abuse (NIDA), National Institutes of Health NIDA Data Share publishes de-identified individual participant datasets, protocols, annotated case report forms, and data dictionaries from completed NIDA-funded clinical trials, primarily from the National Drug Abuse Treatment Clinical Trials Network. Users download data for free after completing a registration agreement and accepting the NIDA Data Share Agreement, without committee review. IPD repository Free registration HDB-0322

AccessClinicalData@NIAID

National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health AccessClinicalData@NIAID provides controlled access to de-identified individual participant-level data from NIAID-supported clinical trials, initially covering COVID-19 and other infectious disease studies. Data are made available to approved users only after execution of a Data Use Agreement between NIAID and the requester's institution. IPD repository By application HDB-0332

ConcertAI — Patient360

ConcertAI Patient360 is ConcertAI's de-identified oncology dataset combining electronic health record, claims, genomic and social determinants data drawn from US cancer centres. Life sciences companies license it for evidence generation, therapeutic development and clinical trial feasibility work. Commercial provider Paid HDB-0335

OM1 — AI Outcomes Platform

OM1 OM1 licenses a de-identified US dataset linking electronic health record, claims, laboratory, mortality and social determinants data into longitudinal patient records. Life sciences companies use it for cohort discovery, evidence generation and clinical trial planning under commercial licence. Commercial provider Paid HDB-0336

Guardant Health — InfinityAI

Guardant Health InfinityAI is Guardant Health's precision-oncology dataset linking longitudinal genomic sequencing results with de-identified clinical records, supporting derivation of endpoints such as overall survival and time to treatment change. It is licensed to life sciences companies through Guardant Health's biopharma division. Commercial provider Paid HDB-0337

Labcorp — Data Solutions

Labcorp Labcorp licenses de-identified longitudinal laboratory and diagnostic testing data from its US network, linked where available to electronic health record and claims data. Life sciences companies use it for retrospective cohort research and prospective data capture under commercial agreement. Commercial provider Paid HDB-0338

Quest Diagnostics — Data Licensing

Quest Diagnostics Quest Diagnostics licenses de-identified laboratory test results and clinical biomarker data drawn from its US testing network. Life sciences companies use it for research, clinical trial design and real-world evidence, with data supplied as custom packages under commercial agreement. Commercial provider Paid HDB-0340

Helix — Research Network

Helix The Helix Research Network licenses clinico-genomic datasets pairing whole-exome sequencing with longitudinal electronic health record and claims data from consented participants recruited through US health system partners. Life sciences companies use it for target discovery and precision medicine research under commercial agreement. Commercial provider Paid HDB-0341

Nashville Biosciences

Nashville Biosciences (Vanderbilt University Medical Center subsidiary) Nashville Biosciences licenses genomic data and linked longitudinal electronic health records derived from the BioVU biorepository. Life sciences companies use it for discovery and post-market research under custom commercial agreements. Commercial provider Paid HDB-0342

Gradient Health

Gradient Health Gradient Health licenses de-identified medical imaging studies together with linked electronic health record, laboratory, pathology and ECG data sourced from partner hospitals. It is used for medical AI development and research, with datasets supplied under commercial agreement. Commercial provider Paid HDB-0343

Carelon Real World Data

Carelon Research (Elevance Health) Carelon Real World Data links closed commercial and Medicare claims with clinical data from outpatient electronic health records, and is operated by Carelon Research, part of Elevance Health. Organisations license access through Carelon Research, which supports study design and provides data samples for evaluation before purchase. Commercial provider Paid HDB-0344

Prognos Health prognosFACTOR

Prognos Health The prognosFACTOR platform aggregates de-identified laboratory, genomic and claims data from multiple contributing sources, with particular depth in oncology and rare disease. Life sciences companies and payers license access through Prognos Health for research, commercial strategy and provider targeting. Commercial provider Paid HDB-0345

Trilliant Health

Trilliant Health Trilliant Health licenses de-identified all-payer claims data spanning commercial, Medicare, Medicare Advantage and Medicaid populations, alongside a national provider directory and negotiated-rate price transparency datasets. Customers use it to analyse referral patterns, market share and competitive position, with delivery through dashboards, direct data feeds and consulting engagements. Commercial provider Paid HDB-0346

Payerset Data Lake

Payerset LLC Payerset licenses normalised machine-readable price transparency files published by US commercial payers and providers, exposing negotiated rates, procedure codes, provider identifiers and rate history. Access is offered through Snowflake Marketplace, cloud storage, REST APIs and custom delivery arrangements. Commercial provider Paid HDB-0347

Veradigm — Health Data

Veradigm LLC Veradigm licenses de-identified ambulatory electronic health record data from US primary care and specialty practices, including unstructured clinical notes processed with natural language processing. Researchers and life sciences companies license either defined cohorts or the full dataset for regulatory, comparative effectiveness and discovery research. Commercial provider Paid HDB-0356

LexisNexis Risk Solutions — Socioeconomic Health Scores

LexisNexis Risk Solutions (RELX) LexisNexis Risk Solutions licenses socioeconomic and social determinants of health attributes and derived risk scores covering the US adult population, compiled from public and commercial record sources. Providers and payers license the data to stratify risk and identify high-need patients where claims data is unavailable. Commercial provider Paid HDB-0357

Socially Determined — SocialScape

Socially Determined SocialScape is Socially Determined's dataset of social determinants of health measures at individual and community level, covering domains such as financial insecurity, housing stability, food access, transport and social isolation. Providers and payers license it to identify at-risk populations, target interventions and measure programme impact. Commercial provider Paid HDB-0358

Verato — hMDM (Healthcare Master Data Management)

Verato Verato licenses a referential identity dataset used to resolve patient, member and provider records across separate healthcare systems. Providers, payers and health information exchanges license it to maintain unified identity records for clinical operations and care coordination. Commercial provider Paid HDB-0359

AnalyticsIQ — PeopleCore

AnalyticsIQ (Alliant) AnalyticsIQ licenses a consumer marketing dataset covering US adults with demographic, lifestyle and social determinants of health attributes, alongside linked healthcare provider audiences. Life sciences companies, payers and providers license it for audience targeting and patient and physician engagement campaigns. Commercial provider Paid HDB-0360

Acxiom — Acxiom Health

Acxiom (Interpublic Group) Acxiom licenses de-identified consumer and healthcare provider audience data built from behavioural and demographic attributes, with claims-derived audiences available for activation. Life sciences companies, payers and agencies license it for audience segmentation and digital campaign targeting. Commercial provider Paid HDB-0361

Experian — Experian Health

Experian Experian Health licenses consumer identity, insurance eligibility and patient financial data alongside consumer health audience segments. Providers and payers license it for patient access, revenue cycle management, identity verification and patient outreach. Commercial provider Paid HDB-0362

Vizient Clinical Data Base

Vizient, Inc. The Vizient Clinical Data Base contains administrative billing data, clinical indicators and risk-adjusted outcome measures contributed by member healthcare organisations. Members access it through dashboards, reporting tools, data downloads and APIs to benchmark clinical and operational performance. Commercial provider Paid HDB-0363

Trella Health

Trella Health Trella Health licenses de-identified Medicare, Medicare Advantage and commercial medical and pharmacy claims data. Healthcare organisations use it to analyse referral patterns, market share and quality measures across acute and post-acute care settings. Commercial provider Paid HDB-0364

Strata Decision Comparative Analytics

Strata Decision Technology Strata Decision Technology's Comparative Analytics holds financial, operational and physician compensation benchmarking data contributed by participating US hospitals. Healthcare organisations use it to compare performance against peers by region and specialty and to support cost and compensation planning. Commercial provider Paid HDB-0373

Premier Healthcare Database

Premier Inc. The Premier Healthcare Database contains de-identified hospital chargemaster, billing, administrative claims, purchasing and electronic health record data contributed by US hospitals and health systems, and is operated by Premier Inc. Researchers and life sciences companies license it for outcomes research, resource utilisation analysis and clinical trial planning. Commercial provider Paid HDB-0374

Inovalon Real-World Data (MORE2 Registry)

Inovalon Inc. Inovalon licenses de-identified closed medical, pharmacy and laboratory claims data spanning commercial, Medicare and Medicaid populations, marketed to life sciences customers as the MORE2 Registry dataset. Access is by commercial licensing for health economics and outcomes research, observational studies and predictive analytics. Commercial provider Paid HDB-0482

ICD-10-CM and ICD-10-PCS

Centers for Disease Control and Prevention (CDC) / Centers for Medicare & Medicaid Services (CMS) ICD-10-CM (Clinical Modification) is the US diagnostic coding system maintained by CDC for classifying diagnoses and reasons for visits in all healthcare settings, while ICD-10-PCS (Procedure Coding System) is the inpatient procedure coding system maintained by CMS. Both replace their ICD-9 predecessors and are the official coding standards for U.S. healthcare billing and reporting. Terminology Open access HDB-0483

NDC National Drug Code Directory

Food and Drug Administration (FDA) The NDC (National Drug Code) Directory is the FDA's official database containing information on active finished and unfinished drugs submitted in structured product labeling files by drug manufacturers. It includes the three-segment NDC number that identifies each drug product and is updated daily with prescription, over-the-counter, approved, unapproved, repackaged, relabeled, and compounded drug products. Terminology Open access HDB-0512

FDAAA TrialsTracker

Bennett Institute for Applied Data Science, University of Oxford A transparency tracker monitoring compliance with the FDA Amendments Act (FDAAA) 2007, which mandates that certain clinical trials report results within a specified timeframe. The platform tracks which organizations are reporting trial outcomes and identifies those with overdue or unreported results. Trial registry Open access HDB-0530

Ontada Oncology Data for HEOR & Research

Ontada (McKesson) Ontada is McKesson's oncology data and provider-education business, and its HEOR and research offering supplies research-ready de-identified clinical data drawn from US community oncology practices using the iKnowMed electronic health record. Life sciences companies and academic researchers license the data to generate real-world evidence, with access arranged commercially through Ontada. Commercial provider Paid HDB-0535

CPT (Current Procedural Terminology)

American Medical Association (AMA) CPT is the standardized procedural coding system maintained by the AMA that describes medical, surgical, and diagnostic services and procedures performed by healthcare providers. CPT codes are widely used for billing and reimbursement under public and private insurance programs in the United States and are updated annually to reflect current clinical practice and medical innovation. Terminology Paid HDB-0546

CorEvitas Registries

CorEvitas (PPD, Thermo Fisher Scientific) CorEvitas, part of PPD within Thermo Fisher Scientific, runs independent longitudinal registries that collect clinician- and patient-reported data in dermatology, gastroenterology, neurology, obesity, pregnancy and rheumatology. Life-sciences companies license the registry data for safety, comparative-effectiveness and outcomes research through a commercial agreement. Commercial provider Paid HDB-0547

Dandelion Health — Multimodal Real-World Data

Dandelion Health Dandelion Health operates a de-identified multimodal dataset from partner US health systems that combines structured electronic health records with clinical notes, ECG waveforms and medical imaging. Life-sciences and clinical-AI developers use it to train and validate algorithms and for research, under a commercial data-access agreement. Commercial provider Credentialed HDB-0548

PicnicHealth — Research Platform

PicnicHealth PicnicHealth assembles longitudinal medical records for consented patients across therapeutic areas, abstracting records from any care setting into a research-ready dataset. Life-sciences sponsors commission cohorts and patient-reported outcome studies on the platform through a commercial agreement. Commercial provider By application HDB-0549

PearlDiver Mariner Database

PearlDiver PearlDiver maintains the Mariner all-payer claims database of longitudinal US billing, diagnosis and procedure records, widely used in orthopaedic and surgical outcomes research. Researchers query it through a web-based tool under a paid licence. Commercial provider Paid HDB-0550

Oracle Health Real-World Data (Life Sciences AI Data Platform)

Oracle Oracle Health Real-World Data is a de-identified longitudinal patient dataset drawn from Oracle Health (formerly Cerner) electronic health records, delivered through the Oracle Life Sciences AI Data Platform. Pharmaceutical and academic research teams use it for cohort discovery, study feasibility, safety monitoring and health-economics research under a commercial agreement. Commercial provider Paid HDB-0551

Clarivate — DRG Fusion

Clarivate DRG Fusion is a modular analytics product from Clarivate that combines US real-world claims and prescription data into commercial insights for life-sciences brand, sales, marketing and market-access teams. Access is by subscription, arranged through a demo request. Commercial provider Paid HDB-0552

Clarivate — DRG Fingertip Foundations (Fingertip Formulary)

Clarivate DRG Fingertip Foundations, the successor to Fingertip Formulary, is Clarivate's pharmacist-validated database of US formulary coverage, restrictions and payer policies sourced from health plans. Market-access, forecasting and commercial teams in life sciences use it by subscription. Commercial provider Paid HDB-0553

Caris Life Sciences — Clinico-Genomic Database

Caris Life Sciences Caris Life Sciences maintains a multimodal oncology database that links whole-exome and whole-transcriptome sequencing and digital pathology from its own testing with matched real-world clinical outcomes, claims and EHR data. Biopharma companies access it through Caris's partnership programmes for target discovery, biomarker and outcomes research. Commercial provider By application HDB-0554

Guardian Research Network

Guardian Research Network Guardian Research Network is a consortium of US community health systems that pools de-identified electronic health records across all disease areas, with an oncology focus. Life-sciences companies engage it for cohort identification, natural-language-processed chart data, trial matching and virtual comparator studies through a commercial agreement. Commercial provider By application HDB-0555

Verana Health (incl. COTA)

Verana Health Verana Health curates de-identified real-world data from medical-society clinical registries in ophthalmology, urology and neurology, and since its January 2026 merger with COTA also holds COTA's curated oncology electronic-health-record data. Life-sciences companies license disease-specific datasets and analytics for trials, regulatory submissions and health-economics research. Commercial provider Paid HDB-0556

N-Power Medicine — Kaleido Registry (ex-Syapse)

N-Power Medicine N-Power Medicine runs the Kaleido Registry, a consented prospective data-collection programme across a community oncology network, which absorbed Syapse's oncologist network and data assets in its December 2024 acquisition. Pharmaceutical sponsors use the research-ready patient data for trial recruitment and prospective external control arms under a commercial agreement. Commercial provider By application HDB-0557

Epic Cosmos

Epic Systems Epic Cosmos is a de-identified dataset assembled by Epic Systems together with a community of health systems that run its electronic health record, pooling longitudinal patient records across hospitals and clinics. Participating Epic customer organizations and their researchers query it for research and clinical insight, and external researchers may request access through the Cosmos site. Commercial provider Credentialed HDB-0558

FAIR Health

FAIR Health (independent nonprofit) FAIR Health, an independent nonprofit, maintains a repository of private-insurance claims from across the United States and is also custodian of Medicare claims data, from which it derives cost benchmarks and datasets. Payers, providers, government agencies, academics and commercial organizations license benchmark modules, custom datasets and research access. Commercial provider Paid HDB-0559

IQVIA PharMetrics Plus

IQVIA IQVIA PharMetrics Plus is a longitudinal database of fully adjudicated US medical and pharmacy claims with enrollment data from national, regional and self-insured health plans, with variants for MedTech and academic use and an optional mortality linkage. Pharmaceutical, medical-device and academic organizations license it for health-economics, outcomes and patient-journey research. Commercial provider Paid HDB-0561

Humana Healthcare Research

Humana Humana Healthcare Research is the in-house research organisation of the US insurer Humana, studying treatment effectiveness, medication adherence, value-based care and health equity in its Medicare Advantage population using Humana's medical, pharmacy and clinical data. It publishes peer-reviewed studies and works with academic and industry partners through research collaborations; there is no self-serve data licensing. Geo-restricted Research database By application HDB-0603

Milliman MedInsight

Milliman MedInsight is Milliman's healthcare analytics and data warehousing platform, which aggregates and normalises a client's own claims, clinical and pharmacy data and enriches it with Milliman's benchmarks, groupers and risk adjusters. It is licensed by payers, ACOs, employers and state Medicaid agencies for benchmarking, risk adjustment and value-based care reporting rather than sold as a dataset. Commercial provider Paid HDB-0604

Turquoise Health

Turquoise Health Turquoise Health collects the hospital and payer price transparency disclosures published under US rate transparency rules and assembles them into searchable rate data, alongside tooling for contract analysis. It is sold to providers, payers and employers for rate benchmarking and contract negotiation, with access arranged commercially. Commercial provider Paid HDB-0605

Serif Health

Serif Health Serif Health builds price transparency datasets from the machine-readable files that US payers and hospitals are required to publish, normalising them into searchable negotiated rate data. It is sold to healthcare organisations through an API and data products under commercial agreement. Commercial provider Credentialed