IPD repositories

HDB-0306

Vivli

Vivli (independent nonprofit) Vivli is a global platform hosting de-identified individual participant data from completed clinical trials contributed by pharmaceutical sponsors, research organizations and CROs. Researchers apply for access to datasets through a controlled-access repository and secure research environment, with priority given to nonprofit and public health research. IPD repository By application HDB-0307

YODA Project

Yale University The Yale Open Data Access Project is a data intermediary that facilitates access to individual participant data from completed clinical trials contributed by pharmaceutical companies and research institutions. Investigators submit research proposals; approved studies gain access to de-identified patient-level datasets for independent analysis and secondary research. IPD repository By application HDB-0308

Project Data Sphere

Project Data Sphere (independent nonprofit) Project Data Sphere is an open-access repository of de-identified patient-level data from late-phase oncology clinical trials, maintained by pharmaceutical sponsors, research institutions, and the PDS research program. Researchers can access datasets and analytical tools free after registration with no research proposal required. IPD repository Free registration HDB-0309

ClinicalStudyDataRequest.com

ClinicalStudyDataRequest.com Consortium ClinicalStudyDataRequest.com is a consortium platform where pharmaceutical sponsors and research organizations list individual participant datasets from completed trials available for researcher access. External investigators submit data-access requests for de-identified datasets; approved requests are facilitated through the platform. IPD repository By application HDB-0310

Infectious Diseases Data Observatory

University of Oxford, Centre for Global Health Research IDDO curates and harmonizes individual participant data from studies of malaria, COVID-19, visceral leishmaniasis, schistosomiasis, and other infectious diseases, including the World-Wide Antimalarial Resistance Network (WWARN) and ISARIC data on COVID-19. De-identified IPD standardized to CDISC is freely available to nonprofit researchers; data inquiries are managed through the platform. IPD repository By application HDB-0311

NHLBI BioLINCC

National Heart, Lung, and Blood Institute (NIH) BioLINCC is the NIH repository for de-identified individual participant data and biospecimens from NHLBI-funded cardiovascular, pulmonary, blood, and sleep disorder studies. Researchers with institutional IRB approval or exemption may request access to datasets through a formal data-access request and data-use agreement process. IPD repository Credentialed HDB-0312

ImmPort

National Institute of Allergy and Infectious Diseases (NIAID) NIH immunology data repository hosting individual participant data from immunology and allergy clinical trials. Researchers register freely to search and download de-identified datasets, or request access to controlled-access studies through the system. IPD repository Free registration HDB-0313

ITN TrialShare

Immune Tolerance Network (NIAID) Immune Tolerance Network repository holding de-identified individual participant data from 27 clinical trials covering transplantation, autoimmunity, allergy, and type 1 diabetes. Researchers create a free account to access de-identified data, explore studies, and perform exploratory analyses. IPD repository Free registration HDB-0314

NIDDK Central Repository

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NIH repository providing access to de-identified individual participant data from diabetes, digestive disease, and kidney disease clinical trials. Researchers identify relevant studies and submit formal data requests to access de-identified datasets through the portal. IPD repository By application HDB-0315

NIMH Data Archive (NDA)

National Institute of Mental Health (NIMH) NIH repository for mental health and neuroscience research hosting de-identified individual participant data from clinical and observational studies. Researchers submit data access requests and sign a Data Use Certification to obtain de-identified datasets from approved studies. IPD repository By application HDB-0316

NICHD DASH

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) NIH Data and Specimen Hub providing access to de-identified individual participant data from child health and maternal-fetal health clinical and population studies. Researchers apply for access through the controlled-access data request process. IPD repository By application HDB-0317

NCTN/NCORP Data Archive

National Cancer Institute (NCI) The NCTN/NCORP Data Archive holds de-identified individual participant data from published phase 2 and phase 3 trials run by NCI's National Clinical Trials Network and Community Oncology Research Program. Researchers request datasets through the archive's online system, with approval governed by data use agreements. IPD repository By application HDB-0318

CPAD (Critical Path for Alzheimer's Disease) / CODR-AD

Critical Path Institute (C-Path) A repository of Alzheimer's disease and mild cognitive impairment clinical trial data from globally executed randomized controlled trials. Researchers and developers apply for access to de-identified, fully standardized patient-level records across 28 studies containing 6,955 individual participant records. IPD repository By application HDB-0320

NIA Aging Research Biobank

National Institute on Aging (NIA), National Institutes of Health The Aging Research Biobank archives and distributes de-identified participant-level clinical data, imaging data, and biospecimens from completed NIA-funded clinical trials and longitudinal studies, including ASPREE, CALERIE, and the Testosterone Trials. Principal investigators register with identity verification, submit a request for materials with a protocol and IRB documentation, and receive data under a signed transfer agreement after scientific review and NIA approval. IPD repository By application HDB-0321

NIDA Data Share

National Institute on Drug Abuse (NIDA), National Institutes of Health NIDA Data Share publishes de-identified individual participant datasets, protocols, annotated case report forms, and data dictionaries from completed NIDA-funded clinical trials, primarily from the National Drug Abuse Treatment Clinical Trials Network. Users download data for free after completing a registration agreement and accepting the NIDA Data Share Agreement, without committee review. IPD repository Free registration HDB-0322

AccessClinicalData@NIAID

National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health AccessClinicalData@NIAID provides controlled access to de-identified individual participant-level data from NIAID-supported clinical trials, initially covering COVID-19 and other infectious disease studies. Data are made available to approved users only after execution of a Data Use Agreement between NIAID and the requester's institution. IPD repository By application